Results 111 to 120 of about 7,058,225 (244)
Journal of Biological Chemistry, 2000 Heat shock protein 70 (HSP70) has been shown to act as an inhibitor of apoptosis. We have also observed an inhibitory effect of HSP70 on apoptotic cell death both in preheated U937 and stably transfected HSP70-overexpressing U937 (U937/HSP70) cells ...
Chun-Ying Li +4 more
semanticscholar +1 more source
The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB [PDF]
, 2006 The tight junction adaptor protein ZO-1 regulates intracellular signaling and cell proliferation. Its Src homology 3 (SH3) domain is required for the regulation of proliferation and binds to the Y-box transcription factor ZO-1-associated nucleic acid ...
Balda, MS, Matter, K, Tsapara, A
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The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke
Expert opinion on therapeutic targets, 2018 Introduction: The 70-kDa heat shock protein (Hsp70) is a cytosolic chaperone which facilitates protein folding, degradation, complex assembly, and translocation. Following stroke, these functions have the potential to lead to cytoprotection, and this has
J. Y. Kim +3 more
semanticscholar +1 more source
A Small Molecule Inhibitor of Inducible Heat Shock Protein 70 (HSP70)
Molecules and Cells, 2009 SUMMARY The multifunctional, stress-inducible, molecular chaperone HSP70 has important roles in aiding protein folding and maintaining protein homeostasis.
J. Leu +4 more
semanticscholar +1 more source
, 2012 Background. Oral verrucous hyperplasia is a precancerous lesion of oral verrucous carcinoma. Methods. This study used immunohistochemistry to examine the expression of p53, murine double minute 2 MDM2, p21, heat shock protein 70 HSP 70, and human ...
林弘斌;王逸平;江俊斌 +1 more
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Hop as an Adaptor in the Heat Shock Protein 70 (Hsp70) and Hsp90 Chaperone Machinery*
Journal of Biological Chemistry, 1998 Hop, an abundant and conserved protein of unresolved function, binds concomitantly with heat shock protein 70 (Hsp70) and Hsp90, participates with heat shock proteins at an intermediate stage of progesterone receptor assembly, and is required for ...
Shi-Ying Chen, David F. Smith
semanticscholar +1 more source
Applied BiosciencesFlavonoids share a common structural framework that serves as a hallmark indicative of their biological activity. In this study, we investigated the effects of two structurally similar flavonoids, fisetin and morin, through independent and combined in ...
Garyfallia Papa +7 more
doaj +1 more source
Терапевтический архив, 2014 AIM: To determine the levels of 70-kDa heat shock protein (HSP70) in urine and anti-HPS70 antibodies (Abs) in serum and to assess their clinical and prognostic value in patients with different forms of chronic glomerulonephritis (CGN)/MATERIAL AND ...
N V Chebotareva +3 more
doaj
Effects of metformin on human monocytic THP-1 cells - Implications for type 2 diabetes mellitus [PDF]
, 2010 Metformin is an anti-hyperglycaemic agent widely prescribed for type 2 diabetes (T2D). Despite decades of clinical use, its exact pharmacological mechanism(s) is yet to be definitively determined.
Tsuei, An-Chi
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Adaptive responses to temperature and photoperiod in neuromuscular transmissionin carcinus maenas (l) [PDF]
, 2004 Neuromuscular synaptic transmission in the ectothermal crab Carcinus maenas was used to assess the extent to which photoperiod affected the attainment of temperature acclimation.
Qari, Suhaila
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