Results 201 to 210 of about 7,058,225 (244)

Carbenoxolone, a new inducer of heat shock protein 70

Life Sciences, 2001
Heat shock protein 70 (Hsp70) is capable of protecting cells, tissues, organs, and animals from a subsequent, normally lethal heating, as well as from numerous disease states. Therefore, it would be of great therapeutic benefit to discover compounds that are clinically safe yet able to induce Hsp70 in patients.
S, Nagayama, H, Jono, H, Suzaki, K, Sakai, E, Tsuruya, I, Yamatsu, Y, Isohama, T, Miyata, H, Kai   +8 more
openaire   +2 more sources

Immunolocalization of heat shock protein 70 in bovine spermatozoa

Andrologia, 2004
Heat shock protein 70 (HSP70) is part of a superfamily of molecular chaperones, which protect cells from chemical and heat shock. The objectives of this study were to determine the presence of HSP70 in bovine spermatozoa and its subcellular localization during different stages of spermatogenesis.
M, Kamaruddin, T, Kroetsch, P K, Basrur, P J, Hansen, W A, King   +4 more
openaire   +2 more sources

Heat‐shock protein 70 expression in the equine cornea

Veterinary Ophthalmology, 2016
AbstractObjectiveExpression of the 70‐kDa heat‐shock protein (HSP70) has been demonstrated in normal canine corneal epithelium, and inducible expression has been suggested to facilitate wound resolution through organized migration, proliferation, and adhesion of the corneal epithelial cells.
Cornelia Peterson, Elizabeth Driskell, David Wilkie, Christopher Premanandan, Ralph Hamor   +4 more
openaire   +2 more sources

Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retina

2018
Heat shock proteins (HSP) belong to a family of stress-induced proteins essential to cell survival. HSP have multiple protective roles through assistance in protein folding, maintaining mitochondrial homeostasis, suppressing proinflammatory cytokines, resisting ischemic damage and protecting cells from apoptotic and necrotic death.
Ting Zhang, Bobak Bahrami, Ling Zhu
openaire   +1 more source

Expression of Heat Shock Protein 70 and Heat Shock Cognate 70 Messenger RNAs in Rat Cortex and Cerebellum After Heat Shock or Amphetamine Treatment

Journal of Neurochemistry, 1991
Abstract: The expression of strictly inducible hsp70 mRNAs and constitutively expressed hsc70 mRNAs was compared in cerebellum and cerebral cortex of control rats, heat‐shocked rats, and rats made hyperthermic with amphetamine. An hsc70‐specific oligonucleotide probe identified a 2.55‐kb mRNA in cerebellum and cerebral cortex of all rats.
E K, Miller, J D, Raese, M, Morrison-Bogorad   +2 more
openaire   +2 more sources

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Nature Cell Biology, 2000
H. Beere, B. Wolf, K. Cain, D. Mosser, A. Mahboubi, T. Kuwana, P. Tailor, R. Morimoto, G. Cohen, D. Green   +9 more
semanticscholar   +1 more source

Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology.

Pharmacology and Therapeutics, 1998
J. Kiang, G. Tsokos
semanticscholar   +1 more source

Heat-shock protein 70 antagonizes apoptosis-inducing factor

Nature Cell Biology, 2001
L. Ravagnan, S. Gurbuxani, S. Susin, C. Maisse, E. Daugas, N. Zamzami, T. Mak, M. Jäättelä, J. Penninger, C. Garrido, G. Kroemer   +10 more
semanticscholar   +1 more source

Heat shock protein 70 potentiates interferon alpha production by plasmacytoid dendritic cells: relevance for cutaneous lupus and vitiligo pathogenesis

British Journal of Dermatology, 2017
C. Jacquemin, J. Rambert, S. Guillet, D. Thiolat, N. Boukhedouni, M. Doutre, A. Darrigade, K. Ezzedine, Patrick Blanco, A. Taïeb, K. Boniface, J. Seneschal   +11 more
semanticscholar   +1 more source

Characterization of heat shock protein 70 transcript from Nilaparvata lugens (Stål): Its response to temperature and insecticide stresses.

Pesticide Biochemistry and Physiology, 2017
K. Lu, Xia Chen, Wenting Liu, Zhichao Zhang, Y. Wang, Keke You, Yue Li, Rong-Bin Zhang, Qiang Zhou   +8 more
semanticscholar   +1 more source