Results 41 to 50 of about 82,921 (299)

Heat accumulation effect during CO2 laser processing of fused silica optics

open access: yesResults in Physics, 2022
The intrinsic heat-affected zone (HAZ) during the microsecond pulsed laser processing significantly affect the surface quality of the fused silica optics.
Chao Tan   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Effect of cerium on welding performance of 700 MPa high-strength steel used in construction machinery

open access: yes工程科学学报, 2020
As the use of high-strength thick plates is increasing in marine engineering, bridge engineering, petroleum pipelines, and other fields, the required performance level of thick welded plates is also increasing.
Bin LU   +3 more
doaj   +1 more source

Effect of Grit Blasting and Thermal Spraying on Microstructure Evolution of P91 Weldment [PDF]

open access: yesArchives of Metallurgy and Materials, 2018
In the present work, studies have been carried out on the variations in the microstructure and hardness of P91 base-metal and welded joint. This variations result from the grit blasting and thermal cycle experienced during the thermal spraying process ...
J.G. Thakare   +4 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

Pengaruh variasi kuat arus dan kecepatan pengelasan terhadap sifat mekanik hasil pengelasan SAW plat baja SS41 grade A

open access: yesJurnal Energi Dan Manufaktur, 2012
Welding is a method used to joint metal or metal alloy that take heat energy from welding machine. On welding process, there is occurred the fusion between base metal with filled metal.
IN Budiarsa, IGN Nitya Santhiarsa
doaj  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Study on the Corrosion Behavior of 7A52 Al Alloy Welded Joint by Electrochemical Method

open access: yesInternational Journal of Electrochemical Science, 2013
Twin-wire metal inert gas arc welding (TMW) was used to join the 7A52 Al alloy plates with the ER 5356 filler. The microstructure observation showed that the joint included four zones, i. e., base metal, heat affected zone, fusion zone and weld zone. The
Chao Yang   +5 more
doaj   +1 more source

Assessment of the Heat Input Effect on the Distribution of Temperature Cycles in the HAZ of S460MC Welds in MAG Welding

open access: yesMetals, 2021
Temperature cycles generated during welding have a significant effect on the changes in the HAZ of welds, regardless of whether these are changes in structure or mechanical properties; however, it is problematic to obtain temperature cycles with ...
Jaromír Moravec   +3 more
doaj   +1 more source

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