Results 71 to 80 of about 1,020,999 (311)

Fire design in safety engineering: likely fire curve for people’s safety [PDF]

, 2018
The present study analyses fire design settings according to Fire Safety Engineering (FSE) for the simulation of fire in civil activities and compares these simulations developed using natural and analytic fire curves.
Grossi, Luca, Lombardi, Mara, Oranges, Nino, Rossi, Giuliano, Sciarretta, Nicolò   +4 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

An Experimental Study on the Fire Spread Rate and Separation Distance between Facing Stores in Passage-Type Traditional Markets

Energies, 2020
Real-scale fire experiments were conducted to understand the fire spread characteristics of the major combustibles handled in traditional markets, a space with high fire risk.
Hong-Seok Yun, Dong-Gun Nam, Cheol-Hong Hwang   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Experimental Investigation of Ventilation Effects on Combustion Efficiency and Heat Release Rate in Small-Scale Compartment Fires

Fire
A series of fire experiments were conducted in a 0.5 m × 0.5 m × 0.5 m room, and a single door-like opening was adopted. The height of the openings was 20 cm, and the width of the openings varied from 10 cm to 30 cm, with ventilation factors ranging from
Weiheng Li, Yong Sheng, Qishuo Liao, Qi Yu, Zhiqiang Xiao, Guo Chen, Hao Wang, Peng Lin   +7 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Burning Properties of Combined Glued Laminated Timber

Fire
This study delved into the combustion properties of combined glulam bonded using polyurethane (PUR) and resorcinol-phenol-formaldehyde (RPF) adhesives.
Tomáš Kytka, Miroslav Gašparík, David Novák, Lukáš Sahula, Elham Karami, Sumanta Das   +5 more
doaj   +1 more source

Electron beam driven alkali metal atom source for loading a magneto-optical trap in a cryogenic environment

, 2011
We present a versatile and compact electron beam driven source for alkali metal atoms, which can be implemented in cryostats. With a heat load of less than 10mW, the heat dissipation normalized to the atoms loaded into the magneto-optical Trap (MOT), is ...
Amsuess, R., Haslinger, S., Hufnagel, C., Koller, Ch., Lippok, N., Majer, J., Schmiedmayer, J., Schneider, S., Verdu, J.   +8 more
core   +2 more sources

Damage of woven composite under translaminar cracking tests using infrared thermography [PDF]

, 2017
The aim of this work is to increase the study of the notch translaminar propagation of the woven structures, using the InfraRed Thermography (IRT).
Bouvet, Christophe, Lisle, Teddy, Margueres, Philippe, Pastor, Marie-Laetitia   +3 more
core   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source