Results 1 to 10 of about 803,685 (299)
HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. [PDF]
Nature Communications, 2019 Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress.
Chen, Xuemei +5 more
core +3 more sources
Prior exposure strongly influences mechanisms underpinning survival of heat shock in <i>Escherichia coli</i>. [PDF]
Front MicrobiolThe heat shock response of Escherichia coli represents a canonical example of how bacteria can recognize a stress and invoke a protective response by altering specific gene regulation.
Yasir M +7 more
europepmc +2 more sources
Heat Shock Differentially Compromises Embryonic Development and Gene Expression in a Mouse Embryoid Body Model System. [PDF]
Animals (Basel)This study established an in vitro model to investigate peri- and post-implantation embryo development under heat shock conditions. In Experiment 1, we compared the gene expression profiles of the three germ layers in in vivo mouse embryos with those of ...
Intawicha P +5 more
europepmc +2 more sources
Heat shock modulates neutrophil motility in zebrafish. [PDF]
PLoS ONE, 2013 Heat shock is a routine method used for inducible gene expression in animal models including zebrafish. Environmental temperature plays an important role in the immune system and infection progression of ectotherms.
Pui-ying Lam +2 more
doaj +1 more source
Transient intracellular acidification regulates the core transcriptional heat shock response
eLife, 2020 Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou +3 more
doaj +1 more source
Frontiers in Physiology, 2020 Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins.
Jisu Jin +7 more
doaj +1 more source
Non-lethal heat shock increased Hsp70 and immune protein transcripts but not Vibrio tolerance in the white-leg shrimp. [PDF]
PLoS ONE, 2013 Non-lethal heat shock boosts bacterial and viral disease tolerance in shrimp, possibly due to increases in endogenous heat shock protein 70 (Hsp70) and/or immune proteins.
Nguyen Hong Loc +5 more
doaj +1 more source
Al-Hayat, 2020 Species, temperature shock duration, fertilization temperature from different climates can cause different hatching results, so it is necessary to do research on the treatment of variations in heat shock at the same temperature, to obtain information ...
Anny Rimalia
doaj +1 more source
Post-transcriptional regulation of the trypanosome heat shock response by a zinc finger protein. [PDF]
PLoS Pathogens, 2013 In most organisms, the heat-shock response involves increased heat-shock gene transcription. In Kinetoplastid protists, however, virtually all control of gene expression is post-transcriptional.
Dorothea Droll +6 more
doaj +1 more source
Scientific Reports, 2021 Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB).
Johanna M. Huusko +14 more
doaj +1 more source