Results 11 to 20 of about 803,685 (299)

Thermodynamics of Heat Shock Response [PDF]

Physical Review Letters, 1999
Production of heat shock proteins are induced when a living cell is exposed to a rise in temperature. The heat shock response of protein DnaK synthesis in E.coli for temperature shifts from temperature T to T plus 7 degrees, respectively to T minus 7 ...
A. Gragarov, A. Hansen, C. A. Gross, D. B. Straus, D. B. Straus, F. C. Neidhardt, G. M. Makhatadze, J. S. McCarthy, K. Tilly, K. Tilly, Kim Sneppen, Kristine Bourke Arnvig, M. T. Morita, P. L. Privalov, S. L. Herendeen, S. Lindquist, S. Pedersen, S. Reeh, Steen Pedersen, Y. Zhou   +19 more
core   +6 more sources

Shock the heat shock network [PDF]

Journal of Clinical Investigation, 2009
The targeting of tumors is made possible through establishing protein signatures specific for each cancer type. The recent recognition of the higher expression levels of HSP90 and its accumulation in tumor cell mitochondria has made the HSP90 network a feasible target for neutralization.
Cigdem, Atay, Serkan, Ugurlu, Nesrin, Ozören   +2 more
openaire   +2 more sources

Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. [PDF]

, 2009
The aim of this study was to determine whether heat-shock pretreatment exerted a protective effect against sorbitol-induced apoptotic cell death in K562, U937 and HeLa cell lines and whether such protection was associated with a decreased cytochrome c
Aventaggiato, Michele, De Martino, Luisa, Di Stefano, Carla, Fiorito, Filomena, Indelicato, Manuela, Marfe, Gabriella, Pucci, Bruna, Russo, Matteo A., Tafani, Marco   +8 more
core   +1 more source

Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance

Reproductive Biology and Endocrinology, 2013
Background While initially sensitive to heat shock, the bovine embryo gains thermal resistance as it progresses through development so that physiological heat shock has little effect on development to the blastocyst stage by Day 5 after insemination ...
Sakatani Miki, Bonilla Luciano, Dobbs Kyle B, Block Jeremy, Ozawa Manabu, Shanker Savita, Yao JiQiang, Hansen Peter J   +7 more
doaj   +1 more source

Hyperthermia increases HSP production in human PDMCs by stimulating ROS formation, p38 MAPK and Akt signaling, and increasing HSF1 activity

Stem Cell Research & Therapy, 2022
Background Human placenta-derived multipotent cells (hPDMCs) are isolated from a source uncomplicated by ethical issues and are ideal for therapeutic applications because of their capacity for multilineage differentiation and proven immunosuppressive ...
Ju-Fang Liu, Po-Chun Chen, Thai-Yen Ling, Chun-Han Hou   +3 more
doaj   +1 more source

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements. [PDF]

, 2019
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Ahringer, Altschul, Ashe, Bailey, Bourque, Brunquell, Casper, Cavrak, Christians, Chuong, Chuong, Contrino, Cook, Cook, Cutter, Esnault, Feschotte, Fierst, Fuentes, Gonsalves, Grabundzija, Grant, Guertin, Gupta, Halfon, Ho, Howe, Howe, Huang, Huang, Hubley, Ito, Jedlicka, Jiang, Johnstone, Jordan, Kanzaki, Kapitonov, Kapitonov, Kent, Kojima, Labbadia, Langmead, Lee, Li, Li, Li, Liu, Love, Mahat, Maman, Mao, Mark, Matys, McClintock, Mendillo, Mortazavi, Narasimhan, Narasimhan, Patro, Perisic, Pontis, R Development Core Team, Rausch, Santos, Schreiner, Shirayama, Slos, Slotkin, Solís, Stevens, Sun, Sundaram, Sundaram, Tajima, Takaki, Thomas, Thomas, Thomas, Todd, Verster, Vihervaara, Weirauch, Wood, Zhang   +84 more
core   +2 more sources

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

Is there a role for HSF1 in viral infections?

FEBS Open Bio, 2022
Cells undergo numerous processes to adapt to new challenging conditions and stressors. Heat stress is regulated by a family of heat shock factors (HSFs) that initiate a heat shock response by upregulating the expression of heat shock proteins (HSPs ...
Antonia Reyes, Areli J. Navarro, Benjamín Diethelm‐Varela, Alexis M. Kalergis, Pablo A. González   +4 more
doaj   +1 more source

Archaebacterial heat-shock proteins [PDF]

The EMBO Journal, 1984
The response to heat shock was examined in seven archaebacterial strains from the genus Halobacterium. Upon heat shock each strain preferentially synthesized a limited number of proteins which fell into three narrow mol. wt. ranges. Further examination of the heat-shock response in H.
C J, Daniels, A H, McKee, W F, Doolittle
openaire   +2 more sources

The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. [PDF]

PLoS ONE, 2013
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the
Rachel Raynes, Kathleen M Pombier, Kevin Nguyen, Jessica Brunquell, Jamie E Mendez, Sandy D Westerheide   +5 more
doaj   +1 more source