Results 241 to 250 of about 799,148 (303)

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Heat shock protein Gp96 (Grp94) in malaria: functional insights at the host-parasite interface and therapeutic perspectives. [PDF]

Front Cell Dev Biol
Djoumoi D, Diouara AAM, Diop M, Nguer CM, Mbengue B, Thiam F.   +5 more
europepmc   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

A bibliometric analysis of research trends and emerging frontiers in heat shock proteins and hepatocellular carcinoma from 2015 to 2025. [PDF]

Discov Oncol
Qiao P, Ruze R, Tulahong A, Zhong K, Lin Y, Cong Y, Shao Y.   +6 more
europepmc   +1 more source

Lower Plasma Antioxidant Defense and Heat Shock Proteins Mark Intra-Amniotic Sludge Ultrasound Finding. [PDF]

J Ultrasound Med
Roberto CCO, Costa-Beber LC, Sulzbacher LM, Dos Santos JB, Bagetti AKKFS, Becker E, Frizzo MN, Heck TG, Ludwig MS.   +8 more
europepmc   +1 more source

Heat shock proteins in hypothermia: a review. [PDF]

Front Mol Biosci
Song SJ, Wu GC, Yi L, Liu X, Jiang MM, Zhang XC, Yin ZF, Gu W, Ruan Y.   +8 more
europepmc   +1 more source

SlATG8f modulates tomato thermotolerance and fruit quality, correlating with changes in autophagy and heat shock-related genes. [PDF]

PLoS One
Cheng Q, Xu W, Wen C, He Z, Song L.
europepmc   +1 more source

Small heat shock protein HSPB5 uses disorder to bind zinc with high affinity. [PDF]

J Biol Chem
Janowska MK, Racigh V, Woods CN, Fornasari MS, Klevit RE.   +4 more
europepmc   +1 more source