Results 11 to 20 of about 474,171 (296)

Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth

open access: yesScientific Reports, 2021
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB).
Johanna M. Huusko   +14 more
doaj   +1 more source

Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible Hsp70Bb promoter in Drosophila melanogaster

open access: yesG3: Genes, Genomes, Genetics, 2023
Heat-shock-inducible expression of genes through the use of heat-inducible promoters is commonly used in research despite leaky expression of downstream genes of interest without targeted induction (i.e. heat shock).
Natalie Warsinger-Pepe   +3 more
doaj   +1 more source

Non-specific protein modifications by a phytochemical induce heat shock response for self-defense. [PDF]

open access: yesPLoS ONE, 2013
Accumulated evidence shows that some phytochemicals provide beneficial effects for human health. Recently, a number of mechanistic studies have revealed that direct interactions between phytochemicals and functional proteins play significant roles in ...
Kohta Ohnishi   +14 more
doaj   +1 more source

Differential expression of heat shock protein 90, 70, 60 in chicken muscles postmortem and its relationship with meat quality [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective The aim of this study was to investigate the expression of heat shock protein (HSP) 90, 70, and 60 in chicken muscles and their possible relationship with quality traits of meat. Methods The breast muscles from one hundred broiler chickens were
Muhan Zhang   +7 more
doaj   +1 more source

Transient intracellular acidification regulates the core transcriptional heat shock response

open access: yeseLife, 2020
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou   +3 more
doaj   +1 more source

Changes in the transcriptome of morula-stage bovine embryos caused by heat shock: relationship to developmental acquisition of thermotolerance

open access: yesReproductive Biology and Endocrinology, 2013
Background While initially sensitive to heat shock, the bovine embryo gains thermal resistance as it progresses through development so that physiological heat shock has little effect on development to the blastocyst stage by Day 5 after insemination ...
Sakatani Miki   +7 more
doaj   +1 more source

A role for glyceraldehyde-3-phosphate dehydrogenase in the development of thermotolerance in Xenopus laevis embryos [PDF]

open access: yes, 1988
During heat shock, Xenopus laevis embryos exhibit an increase in the rate of accumulation of lactate and a loss of ATP relative to non-heat- shocked control embryos.
Browder, Leon W., Nickells, Robert W.
core   +2 more sources

Expression of Hsp72 in Lymphocytes in Patients with Febrile Convulsion

open access: yesKaohsiung Journal of Medical Sciences, 2005
The pathophysiology of febrile convulsion, the most common childhood neurologic disease, remains unclear. In this study, we investigated what role a heat shock protein plays in this disease.
Lung-Chang Lin
doaj   +1 more source

Heat shock induces expression of OSTC/DC2, a novel subunit of oligosaccharyltransferase, in vitro and in vivo

open access: yesKaohsiung Journal of Medical Sciences, 2014
Mammalian oligosaccharyltransferase complex subunit OSTC/DC2 protein has recently been shown to be a new subunit of the oligosaccharyltransferase; however, its physiological role is still unclear.
Chien-Ming Chen   +7 more
doaj   +1 more source

Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines. [PDF]

open access: yesPLoS ONE, 2012
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones.
Guilian Xu   +6 more
doaj   +1 more source

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