Results 41 to 50 of about 5,347,852 (306)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Heat shock protein and heat shock factor 1 expression and localization in vaccinia virus infected human monocyte derived macrophages

Journal of Inflammation, 2005
Background Viruses remain one of the inducers of the stress response in the infected cells. Heat shock response induced by vaccinia virus (VV) infection was studied in vitro in human blood monocyte derived macrophages (MDMs) as blood cells usually ...
Dziedzic Jakub, Slezak Kinga, Guzik Krzysztof, Kowalczyk Aleksandra, Rokita Hanna   +4 more
doaj   +1 more source

Proteomic analysis of the heat shock and acclimation responses of Cyanobacteria [PDF]

, 2005
The cyanobacterium Synechocystis sp. PCC 6803 is a model experimental organism for proteomic research because its entire genomic sequence is available and cyanobacteria have high adaptive potential towards a variety of environmental stresses.
Hall, John James
core  

Late onset of the serological response against the 18 kDa small heat shock protein of Mycobacterium ulcerans in children [PDF]

, 2014
A previous survey for clinical cases of Buruli ulcer (BU) in the Mapé Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans.
Miriam Bolz, Arianna Andreoli, Pritchard, James, Yeboah-Manu, Dorothy, Amanda Ross, Gerd Pluschke, Jacques C. Minyem (421866), Amanda Ross (187821), Alphonse Um Boock (267187), Ross, Amanda, James Pritchard, Katharina Röltgen, Dorothy Yeboah-Manu (120059), Jacques C. Minyem, Eric Koka, Um Boock, Alphonse, Kobina A. Ampah, Ampah, Kobina A., Andreoli, Arianna, Samuel Y. Aboagye, Noumen, Djeunga, Kobina A Ampah, Martin W. Bratschi (309715), Djeunga Noumen (421870), Bolz, Miriam, Miriam Bolz (309717), Aboagye, Samuel Y., Alphonse Um Boock, James Pritchard (543790), A Ross, Röltgen, Katharina, Bratschi, Martin W., Gerd Pluschke (7855), Katharina Röltgen (120045), Minyem, Jacques C., Martin W Bratschi, Djeunga Noumen, Eric Koka (567714), Koka, Eric, Dorothy Yeboah-Manu, Kobina A. Ampah (567713), Jacques C Minyem, Martin W. Bratschi, Samuel Y. Aboagye (567712), Arianna Andreoli (543789), Pluschke, Gerd, Samuel Y Aboagye   +46 more
core   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Systemic analysis of heat shock response induced by heat shock and a proteasome inhibitor MG132. [PDF]

PLoS ONE, 2011
The molecular basis of heat shock response (HSR), a cellular defense mechanism against various stresses, is not well understood. In this, the first comprehensive analysis of gene expression changes in response to heat shock and MG132 (a proteasome ...
Hee-Jung Kim, Hye Joon Joo, Yung Hee Kim, Soyeon Ahn, Jun Chang, Kyu-Baek Hwang, Dong-Hee Lee, Kong-Joo Lee   +7 more
doaj   +1 more source

Regulation and physiological function of proteins for heat tolerance in cowpea (Vigna unguiculata) genotypes under controlled and field conditions

Frontiers in Plant Science, 2022
The expression of heat shock proteins is considered a central adaptive mechanism to heat stress. This study investigated the expression of heat shock proteins (HSPs) and other stress-protective proteins against heat stress in cowpea genotypes under field
Tonny I. Selinga, Sipho T. Maseko, Hawwa Gabier, Mohammed S. Rafudeen, A. Muthama Muasya, Olivier Crespo, John B. O. Ogola, Alex J. Valentine, Carl-Otto Ottosen, Eva Rosenqvist, Samson B. M. Chimphango   +10 more
doaj   +1 more source

Heat shock proteins in bacilli [PDF]

Journal of Bacteriology, 1985
Five strains of bacilli, including a nonsporulating strain, when heat shocked, accelerated the synthesis of a specific subset of proteins. The major heat shock protein in all bacilli had a molecular weight of 66,000. The response persisted for at least 40 min and could be eliminated upon a shift down to 37 degrees C.
U N, Streips, F W, Polio
openaire   +2 more sources

The Development of ELISA and SPR-Based Immunoassays for the Detection of Heat Shock Proteins. [PDF]

, 2009
Heat shock proteins (Hsps) are highly conserved molecules in all eukaryotes and prokaryotes. They are named on the basis of their molecular weight and their synthesis is up-regulated by stress conditions such as inflammation, oxidative stress and ...
Gong, Bei
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source