Results 41 to 50 of about 467,674 (297)

Alterations in the mitochondrial proteome of neuroblastoma cells 2 in response to complex 1 inhibition [PDF]

, 2011
Increasing evidence points to mitochondrial dysfunction in Parkinson's disease (PD) associated with complex I dysfunction, but the exact pathways which lead to cell death have not been resolved.
Billett, EE, Burté, F, De Girolamo, LA, Hargreaves, AJ   +3 more
core   +1 more source

Regulation and physiological function of proteins for heat tolerance in cowpea (Vigna unguiculata) genotypes under controlled and field conditions

Frontiers in Plant Science, 2022
The expression of heat shock proteins is considered a central adaptive mechanism to heat stress. This study investigated the expression of heat shock proteins (HSPs) and other stress-protective proteins against heat stress in cowpea genotypes under field
Tonny I. Selinga, Sipho T. Maseko, Hawwa Gabier, Mohammed S. Rafudeen, A. Muthama Muasya, Olivier Crespo, John B. O. Ogola, Alex J. Valentine, Carl-Otto Ottosen, Eva Rosenqvist, Samson B. M. Chimphango   +10 more
doaj   +1 more source

Hopf bifurcation in a gene regulatory network model: Molecular movement causes oscillations [PDF]

, 2015
Gene regulatory networks, i.e. DNA segments in a cell which interact with each other indirectly through their RNA and protein products, lie at the heart of many important intracellular signal transduction processes.
Chaplain, M, Ptashnyk, M, Sturrock, M
core   +1 more source

Hspb1 inhibits microglial ferroptosis and pro-inflammatory activation to alleviate cerebral ischemia/reperfusion injury in mice

Neural Regeneration Research
Heat shock protein beta-1 may be involved in regulating ferroptosis in cells. The expression of heat shock protein beta-1 is upregulated after stroke; however, the underlying mechanism of action of heat shock protein beta-1 in cerebral ischemia ...
Weilong Hua, Hongye Xu, Rundong Chen, Yiyong Zeng, Lei Zhang, Yongxin Zhang, Xiaoxi Zhang, Yongwei Zhang, Hongjian Zhang, Jianmin Liu, Pengfei Yang   +10 more
doaj   +1 more source

Involvement of heat shock proteins 60 in acetyl salicylic acid radioprotection of Albino rat submandibular salivary gland

Journal of Radiation Research and Applied Sciences, 2015
The radioprotective effect of acetyl salicylic acid against radiation injury to rat salivary glands was reported but its interrelationship with the expression of heat shock protein 60; an endogenous cytoprotectant against various stressful stimuli has ...
D.G. Mohamed, R.M. Amin
doaj   +1 more source

Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius

mBio, 2023
High-temperature stress is critical for all organisms and induces a profound cellular response. For Crenarchaeota, little information is available on how heat shock affects cellular processes and on how this response is regulated.
Rani Baes, Felix Grünberger, Sébastien Pyr dit Ruys, Mohea Couturier, Sarah De Keulenaer, Sonja Skevin, Filip Van Nieuwerburgh, Didier Vertommen, Dina Grohmann, Sébastien Ferreira-Cerca, Eveline Peeters   +10 more
doaj   +1 more source

Hsp70 in mitochondrial biogenesis [PDF]

, 1994
The family of hsp70 (70 kilodalton heat shock protein) molecular chaperones plays an essential and diverse role in cellular physiology, Hsp70 proteins appear to elicit their effects by interacting with polypeptides that present domains which exhibit non ...
A. Tzagoloff, A. Tzagoloff, A.J. Caplan, A.J. Caplan, B.D. Gambill, B.S. Glick, C.K. Suzuki, D. Ang, D. M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.M. Cyr, D.P. Atencio, E. Ikeda, E. Kutejová, E.A. Craig, E.A. Craig, F.-U. Hartl, G.S.P. Groot, H.R.B. Pelham, J. Ostermann, J. Rassow, J.F. Dice, J.P. Hendrick, K. Liberek, L. Dyck van, M. Eilers, M. Kiebler, M. Schleyer, M.-J. Gething, M.Y. Cheng, N. Rowley, N. Wang, P. Borst, P. Terpstra, P.-J. Kang, R. A. Stuart, R.A. Stuart, R.A. Stuart, R.B. Deshaies, R.G. Hadikusumo, R.J. Nelson, R.P. Beckman, S. Lindquist, S. Rospert, S.T. Hwang, T. Langer, U.C. Manning-Krieg, W. Neupert, W. Neupert, W. Voos, W.J. Chirico, Z. Xia   +53 more
core   +1 more source

Absence of ataxin-3 leads to enhanced stress response in C. elegans. [PDF]

PLoS ONE, 2011
Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway.
Ana João Rodrigues, Andreia Neves-Carvalho, Andreia Teixeira-Castro, Anne Rokka, Garry Corthals, Elsa Logarinho, Patrícia Maciel   +6 more
doaj   +1 more source

The Expression of Heat Shock Protein (Hsp) 25 at Compression and Tension Area DuringAlveolar Bone Remodeling [PDF]

, 2012
The activation of orthodontic appliance will generate mechanical force. This forceis used to depress tooth and the tissues surrounding it then stimulates alveolarbone remodeling. Alveolar bone remodeling is divided into compression andtension area.
Amin, M. N. (Muhammad)
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source