Results 51 to 60 of about 465,173 (296)

CUL-6/cullin ubiquitin ligase-mediated degradation of HSP-90 by intestinal lysosomes promotes thermotolerance

open access: yesCell Reports
Summary: Heat shock can be a lethal stressor. Previously, we described a CUL-6/cullin-ring ubiquitin ligase complex in the nematode Caenorhabditis elegans that is induced by intracellular intestinal infection and proteotoxic stress and that promotes ...
Mario Bardan Sarmiento   +3 more
doaj   +1 more source

CLINICAL SIGNIFICANCE OF SERUM AND URINARY HEAT SHOCK PROTEIN 70 LEVEL ASSESSMENT IN PATIENTS WITH CHRONIC GLOMERULONEPHRITIS

open access: yesAlʹmanah Kliničeskoj Mediciny, 2016
The levels of urinary heat shock protein-70 and serum antibodies to the heat shock protein-70 were assessed in 79 patients with different course variants of the chronic glomerulonephritis. The indices studied were higher in patients with an active course
N. V. Chebotaryova   +3 more
doaj   +1 more source

Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor

open access: yesFrontiers in Microbiology, 2022
Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of heat shock sigma factors and activation of genes normally repressed ...
Yehong Huang   +12 more
doaj   +1 more source

Electro-hyperthermia in Oncology [PDF]

open access: yes, 2001
Hyperthermia is a rapidly developing treatment method in oncology. The classical effect is based on well-focused energy absorption targeting the malignant tissue.
Szász, András   +2 more
core  

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis [PDF]

open access: yes, 1989
Mitochondrial heat-shock protein hsp60 functions in the folding of proteins imported into mitochondria. Folding occurs at the surface of hsp60 in an ATP-mediated reaction, followed by release of the bound polypeptides.
Hartl, Franz-Ulrich   +3 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Mechanism of protonophores-mediated induction of heat-shock response in Escherichia coli

open access: yesBMC Microbiology, 2009
Background Protonophores are the agents that dissipate the proton-motive-force (PMF) across E. coli plasma membrane. As the PMF is known to be an energy source for the translocation of membrane and periplasmic proteins after their initial syntheses in ...
Saha Swati   +3 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai   +2 more
wiley   +1 more source

Heat Shock Protein Augmentation of Root Hot Water Extract on Adipogenic Differentiation in Murine 3T3-L1 Preadipocytes [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2016
There is a high association of heat shock on the alteration of energy and lipid metabolism. The alterations associated with thermal stress are composed of gene expression changes and adaptation through biochemical responses.
Wenchie Marie L. Lumbera   +3 more
doaj   +1 more source

Development of Sustainable MgO–C Refractories Using MgO–C Recyclates and a Novel Eco‐Friendly Fructose–Tannin Binder Crosslinked With Citric Acid

open access: yesAdvanced Engineering Materials, EarlyView.
This study develops sustainable MgO–C refractories using recycled materials and eco‐friendly fructose–tannin binders. The enhanced performance of citric acid as a cross‐linker and functional additives on mechanical and thermomechanical properties was examined. Characterization included strength tests, immersion trials, and microstructural and inclusion
Dinesh K. Gunasekar   +7 more
wiley   +1 more source

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