Results 91 to 100 of about 413,998 (350)

Differential expression of heat shock protein 70 (HSP70) and heat shock cognate protein 70 (HSC70) in human epidermis

Archives of Dermatological Research, 1994
Autoimmunity and microbial agents have been suggested as playing a pathogenetic role in psoriasis. Since immune responses to microbial infections are often directed towards heat shock proteins (HSP), we investigated the expression of three HSP families in normal and inflamed human skin. Specimens from ten patients with psoriasis and three patients with
Boehncke, Wolf-Henning, Dahlke, A., Zollner, Thomas Matthias, Sterry, Wolfram   +3 more
openaire   +3 more sources

Cold cardioplegic arrest enhances heat shock protein 70 in the heat-shocked rat heart [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2001
Myocardial content of the 70-kd heat shock protein has been found to correlate with improved cardiac recovery after ischemia, but the mechanisms and conditions that regulate its level, particularly under clinical conditions, are unclear. The aim of this study was to assess the effect of hypothermic cardioplegic arrest and reperfusion on the expression ...
Gray, Caroline C., Amrani, Mohamed, Smolenski, Ryszard T., Nakamura, Koki, Yacoub, Magdi H.   +4 more
openaire   +2 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. [PDF]

PLoS ONE, 2014
Acute starvation, which is frequently observed in clinical practice, sometimes augments the cytolytic activity of natural killer cells against neoplastic cells. In this study, we investigated the molecular mechanisms underlying the enhancement of natural
Vu T A Dang, Kazuaki Tanabe, Yuka Tanaka, Noriaki Tokumoto, Toshihiro Misumi, Yoshihiro Saeki, Nobuaki Fujikuni, Hideki Ohdan   +7 more
doaj   +1 more source

Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 [PDF]

, 2020
Cancer therapeutics: Extending a drug's reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment.
Chae, Young Chan, Hong, Jun-Hee, Hu, Sung, Kang, Byoung Heon, Kim, So Yeon, Lee, Ji-Eun, Nam, Dougu, Park, Hye-Kyung, Park, Jong Bae, Yoon, Nam Gu, Yoon, Sora   +10 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Identification of an exported heat shock protein 70 in Plasmodium falciparum

Parasite, 2013
Host cell remodelling is a hallmark of malaria pathogenesis. It involves protein folding, unfolding and trafficking events and thus participation of chaperones such as Hsp70s and Hsp40s is well speculated.
Grover Manish, Chaubey Shweta, Ranade Shatakshi, Tatu Utpal   +3 more
doaj   +1 more source

Neonatal feed restriction modulates circulating levels of corticosterone and expression of glucocorticoid receptor and heat shock protein 70 in aged Japanese quail exposed to acute heat stress. [PDF]

, 2011
This study aimed to determine the effect of neonatal feed restriction on plasma corticosterone concentration (CORT), hippocampal glucocorticoid receptor (GR) expression, and heat shock protein (Hsp) 70 expression in aged male Japanese quail subjected to ...
A. F., Soleimani, Abdul Rahim, Raha, Idrus, Zulkifli, Omar, Abdul Rahman   +3 more
core   +1 more source

Binding of Heat-Shock Protein 70 (hsp70) to Tubulin

Archives of Biochemistry and Biophysics, 1994
Binding of heat-shock protein (hsp70) to polymerized tubulin has been investigated by in vitro experiments. The tubulin region involved in binding to hsp70 corresponds to the carboxy-terminal residues 431-444, also involved in the association with other microtubule-associated proteins (MAPs).
Sánchez, Carlos, Padilla, Rodolfo, Paciucci, Rosanna, Zabala, Juan Carlos, Ávila, Jesús   +4 more
openaire   +3 more sources

Anti–Heat Shock Protein 70 Antibodies in Meniere's Disease [PDF]

The Laryngoscope, 2000
AbstractObjectives To determine the prevalence of anti–heat shock protein 70 (anti‐HSP70) antibodies in patients with Meniere's disease and healthy subjects and to probe the relationship between antibody status and clinical features of Meniere's disease.Study Design Prospective cohort study of consecutive consenting patients with Meniere's disease ...
S D, Rauch, D, Zurakowski, D B, Bloch, K J, Bloch   +3 more
openaire   +2 more sources