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Regulatory domain of human heat shock transcription Factor-2 is not regulated by hemin or heat shock
Journal of Cellular Biochemistry, 1999Heat shock transcription factor 2 (HSF-2) activates transcription of heat shock proteins in response to hemin in the human erythroleukemia cell line, K562. To understand the regulation of HSF-2 activation, a series of deletion mutants of HSF-2 fused to the GAL-4 DNA binding domain were generated.
Z, Zhu, N F, Mivechi
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Bending of promoter DNA on binding of heat shock transcription factor
Nature, 1986The Drosophila heat-shock transcription factor (HSTF) has been shown to bind to three domains of the heat shock protein 70 gene (hsp 70) control region. The most critical of these for transcriptional activation appears to be the one closest to the TATA-homology region.
D J, Shuey, C S, Parker
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Expression and Purification of Human Heat-Shock Transcription Factor 1
Protein Expression and Purification, 1997Heat-shock factor 1 (HSF1) is a 57-kDa cytoplasmic protein which binds to the promoters of heat-shock genes and activates transcription during heat shock. We describe here the expression and purification of the 529 amino acids form of human HSF1. We designed a new and complete purification protocol involving ammonium sulfate precipitation, heparin ...
Soncin, Fabrice +2 more
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In vitro activation of heat shock transcription factor by 4-hydroxynonenal
Chemico-Biological Interactions, 1992In the activation of eukaryotic heat shock genes, the acquisition of a binding ability to specific DNA sequence by a transcriptional activator, heat shock factor (HSF), is believed to be a crucial step. The induction of this new DNA binding activity of HSF is also obtained in a cell-free system (in vitro activation) by hyperthermia or at physiological ...
F, Cajone, M, Crescente
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Regulation of the heat shock response by heat shock transcription factors
2006Ville Hietakangas, Lea Sistonen
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Multiple functions ofDrosophilaheat shock transcription factorin vivo
EMBO Journal, 1997Carl Wu, Mark A Mortin
exaly
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 2007
Scott Powers +2 more
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Scott Powers +2 more
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