Results 101 to 110 of about 7,127,110 (304)
, 2017 Heat stress is one of the most important environmental stressors that reduce productivity in animal breeding. The productivity of farm animals is significantly reduced due to temperature increases. As a result, significant economic losses occur during the summer months.
Sireli, Halit Deniz +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Heat stress during flowering in cereals - effects and adaptation strategies.
New Phytologist, 2020 Heat stress during flowering has differential impact on male and female reproductive organs viability leading to yield losses in field crops. Unlike flooded rice, dryland cereals such as sorghum, pearl millet and wheat have optimized their flower opening
S. Jagadish
semanticscholar +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Human temperature regulation under heat stress in health, disease, and injury.
Physiological Reviews, 2022 M. Cramer +3 more
semanticscholar +1 more source
PLoS ONE, 2020 Heat stress along with low water availability at reproductive stage (terminal growth phase of wheat crop) is major contributing factor towards less wheat production in tropics and sub-tropics. Flag leaf plays a pivotal role in assimilate partitioning and
A. Sattar +7 more
semanticscholar +1 more source
Interaction of Aflatoxicosis with Heat Stress ,
Poultry Science, 1975 An earlier study reported an increased resistance of chickens to an acute lethal heating episode (43 degrees C. and 45% relative humidity) during aflatoxicosis. This varies from other stresses investigated which interact with aflatoxicosis to make chickens more sensitive to the stress factor.
R D, Wyatt, P, Thaxton, P B, Hamilton
openaire +2 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source