Results 81 to 90 of about 610,120 (308)

carcasan/Light-Heat-stress: Light-Heat-Stress

, 2023
No description ...
Carolina Castro-Sanguino
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

HEAT STRESS IN RUMINANTS

, 2017
Heat stress is one of the most important environmental stressors that reduce productivity in animal breeding. The productivity of farm animals is significantly reduced due to temperature increases. As a result, significant economic losses occur during the summer months.
Sireli, Halit Deniz, Tutkun, Muhittin, Tatar, Ali Murat, Tuncer, Selcuk Seckin   +3 more
openaire   +3 more sources

Heat stress in horses: a literature review

, 2023
Healthy adult horses can balance accumulation and dissipation of body heat to maintain their body temperature between 37.5 and 38.5 °C, when they are in their thermoneutral zone (5 to 25 °C). However, under some circumstances, such as following strenuous
Rebeka R. Zsoldos, Narayan, Edward, Sole-Guitart, Albert, John B. Gaughan, Zsoldos, Rebeka R, Hyungsuk Kang, Edward Narayan, Gaughan, John B, Albert Sole-Guitart, A. Judith Cawdell-Smith, Kang, Hyungsuk, Cawdell-Smith, A Judith   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Time-series transcriptomic analysis of flower tissue during heat stress in heat-resilient and heat-sensitive Brassica napus L.

Frontiers in Genetics
Brassica napus a cool-season oilseed crop, is an important source of edible oil and biofuel. Heat stress during the reproductive stage poses a serious threat to its productivity, but little is known about the gene networks involved in the heat stress ...
Xiaojie Hu, Xiaojie Hu, Sheng Chen, Sheng Chen, Xiaoke Ping, Xiaoke Ping, Kadambot H. M. Siddique, Kadambot H. M. Siddique, Wallace A. Cowling, Wallace A. Cowling   +9 more
doaj   +1 more source

Interaction of Aflatoxicosis with Heat Stress ,

Poultry Science, 1975
An earlier study reported an increased resistance of chickens to an acute lethal heating episode (43 degrees C. and 45% relative humidity) during aflatoxicosis. This varies from other stresses investigated which interact with aflatoxicosis to make chickens more sensitive to the stress factor.
R D, Wyatt, P, Thaxton, P B, Hamilton
openaire   +2 more sources

Study of yield components under heat stress conditions in wheat

, 2013
High temperature tolerance can be characterised by measuring various plant productivity traits in different developmental stages. The present work investigated the effect of exposure to high temperature (30-35°C) at first node appearance, during ...
Balla, Krisztina, Veisz, Ottó Bálint, Karsai, Ildikó, Kiss, Tibor, Bencze, Szilvia   +4 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Breeding for improved heat tolerance in dairy cattle: Methods, challenges, and progress*

JDS Communications
Heat tolerance in dairy cattle has likely deteriorated over time due to unfavorable genetic correlations between milk production level and heat tolerance, with stronger deterioration in later parities.
Ignacy Misztal, Luiz F. Brito, Daniela Lourenco   +2 more
doaj   +1 more source