Results 111 to 120 of about 7,306,204 (405)
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Contiguous US summer maximum temperature and heat stress trends in CRU and NOAA Climate Division data plus comparisons to reanalyses. [PDF]
, 2018 Warming is a major climate change concern, but the impact of high maximum temperatures depends upon the air's moisture content. Trends in maximum summertime temperature, moisture, and heat index are tracked over three time periods: 1900-2011, 1950-2011 ...
Grotjahn, Richard, Huynh, Jonathan
core
Temperature, 2020 The kidneys’ integrative responses to heat stress aid thermoregulation, cardiovascular control, and water and electrolyte regulation. Recent evidence suggests the kidneys are at increased risk of pathological events during heat stress, namely acute ...
Christopher L. Chapman +5 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Animals, 2020 The increasing trend of global warming has affected the livestock industry through the heat stress, especially in poultry. Therefore, a better understanding of the mechanisms of heat stress in poultry would be helpful for maintaining the poultry ...
Da Rae Kang, Kwan Seob Shim
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
BMC Plant Biology, 2012 Background Grapes are a major fruit crop around the world. Heat stress can significantly reduce grape yield and quality. Changes at the molecular level in response to heat stress and subsequent recovery are poorly understood.
Liu Guo-Tian +9 more
doaj +1 more source
Physiological Studies of Heat Stress Acclimation During a Specific Exercise Regimen [PDF]
, 1982 Eleven subjects were used to determine if the exercise regimen of racquetball could be used as a heat stress acclimator. Core temperature, skin temperature, sweat production, and weight loss were recorded during a racquetball match.
Johnson, Alan M., Morgans, Leland F.
core +2 more sources
Thermal imaging on simulated faults during frictional sliding [PDF]
, 2006 Heating during frictional sliding is a major component of the energy budget of earthquakes and represents a potential weakening mechanism. It is therefore important to investigate how heat dissipates during sliding on simulated faults. We present results
Gundersen, Olav +2 more
core +5 more sources
Journal of Animal Science and Biotechnology, 2020 Heat stress is known to affect follicular dynamics, oocyte maturation, and fertilization by impairing steroidogenic ability and viability of bovine granulosa cell (bGCs).
Adnan Khan +7 more
semanticscholar +1 more source