Results 81 to 90 of about 1,636,472 (355)

Transcriptomic analysis of grape (Vitis vinifera L.) leaves during and after recovery from heat stress

open access: yesBMC Plant Biology, 2012
Background Grapes are a major fruit crop around the world. Heat stress can significantly reduce grape yield and quality. Changes at the molecular level in response to heat stress and subsequent recovery are poorly understood.
Liu Guo-Tian   +9 more
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Contiguous US summer maximum temperature and heat stress trends in CRU and NOAA Climate Division data plus comparisons to reanalyses. [PDF]

open access: yes, 2018
Warming is a major climate change concern, but the impact of high maximum temperatures depends upon the air's moisture content. Trends in maximum summertime temperature, moisture, and heat index are tracked over three time periods: 1900-2011, 1950-2011 ...
Grotjahn, Richard, Huynh, Jonathan
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Breeding for improved heat tolerance in dairy cattle: Methods, challenges, and progress*

open access: yesJDS Communications
Heat tolerance in dairy cattle has likely deteriorated over time due to unfavorable genetic correlations between milk production level and heat tolerance, with stronger deterioration in later parities.
Ignacy Misztal   +2 more
doaj   +1 more source

Proteomic Analysis of the Protective Effect of Early Heat Exposure against Chronic Heat Stress in Broilers

open access: yesAnimals, 2020
The increasing trend of global warming has affected the livestock industry through the heat stress, especially in poultry. Therefore, a better understanding of the mechanisms of heat stress in poultry would be helpful for maintaining the poultry ...
Da Rae Kang, Kwan Seob Shim
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Time-series transcriptomic analysis of flower tissue during heat stress in heat-resilient and heat-sensitive Brassica napus L.

open access: yesFrontiers in Genetics
Brassica napus a cool-season oilseed crop, is an important source of edible oil and biofuel. Heat stress during the reproductive stage poses a serious threat to its productivity, but little is known about the gene networks involved in the heat stress ...
Xiaojie Hu   +9 more
doaj   +1 more source

Modelling linered engine blocks [PDF]

open access: yes, 1991
Factors that affect heat transfer in the linered aluminium engine block are examined to determine their importance. Conduction is found to be the dominant mode of heat transfer, and the interface is characterised as imperfect contact if there are no ...
Ha, J.
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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