Results 81 to 90 of about 7,306,204 (405)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Heat stress and stallion fertility

Journal of Animal Science and Technology, 2023
The threat posed by increased surface temperatures worldwide has attracted the attention of researchers to the reaction of animals to heat stress. Spermatogenesis in animals such as stallions is a temperature-dependent process, ideally occurring at temperatures slightly below the core body temperature.
Muhammad Shakeel, Minjung Yoon
openaire   +3 more sources

Heat stress survey

California Agriculture, 1979
The cattle and milk-production losses caused by tropical storm Doreen enabled dairymen to evaluate the effectiveness of various heat-stress-reducing devices.
J Oliver, H Hellman, S Bishop, C Pelissier, L Bennett   +4 more
doaj  

ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana

BMC Biology, 2022
Background Heat stress is a major abiotic stress affecting the growth and development of plants, including crop species. Plants have evolved various adaptive strategies to help them survive heat stress, including maintaining membrane stability, encoding ...
Xia Chen, Huidan Xue, Liping Zhu, Huiqin Wang, Hao Long, Jun Zhao, Funing Meng, Yunfei Liu, Yuan Ye, Xiaomin Luo, Zhi Liu, Guanghui Xiao, Shengwei Zhu   +12 more
doaj   +1 more source

The Skn7 Response Regulator of \u3ci\u3eSaccharomyces cerevisiae\u3c/i\u3e Interacts with Hsf1 In Vivo and Is Required for the Induction of Heat Shock Genes by Oxidative Stress [PDF]

, 2000
The Skn7 response regulator has previously been shown to play a role in the induction of stress-responsive genes in yeast, e.g., in the induction of the thioredoxin gene in response to hydrogen peroxide.
Erkine, Alexander M., Gross, David S., Johnson, Anthony L., Johnston, Leland H., Makino, Kozo, Morgan, Brian, Raitt, Desmond C.   +6 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Heat stress response and heat stress transcription factors

Journal of Biosciences, 1998
Expression of heat shock protein (HSP)-coding genes is controlled by heat stress transcription factors (Hsfs). They are structurally and functionally conserved throughout the eukaryotic kingdom. In addition to the DNA-binding domain with the helix-turn-helix motif essential for DNA recognition, three functional parts in the C-terminal activator domain ...
Klaus-Dieter Scharf, Ingo Höhfeld, Lutz Nover   +2 more
openaire   +1 more source

Heat stress and copper supplementation in pigs

California Agriculture, 1989
Controlled feeding trials at UC Davis found no connection between temperature stress and response to copper supplementation, but confirmed overall effects of heat stress on pigs.
H Heitman, S Morrison, K Parker
doaj  

Label-Free Comparative Proteomics Analysis Revealed Heat Stress Responsive Mechanism in Hypsizygus marmoreus

Frontiers in Microbiology, 2021
Heat stress is an important adverse environmental stress that influences the growth and development of Hypsizygus marmoreus (white var.). However, the molecular basis of heat stress response in H. marmoreus remains poorly understood. In this study, label-
Lili Xu, Lizhong Guo, Hao Yu
doaj   +1 more source

Examining Stress Relaxation in a Dissimilar Metal Weld Subjected to Postweld Heat Treatment [PDF]

, 2018
Dissimilar metal welds are often required in nuclear power plants to join components made from austenitic steels to those from ferritic steels, particularly in fast breeder reactor plants, in order to join the intermediate heat exchanger to the steam ...
Abburi Venkata, Abburi Venkata, Brown, Chuvas, Dong, Funderburk., Hossain, Hosseinzadeh, Kwon, Leggatt., McLean, Muransky, Newell, Olson, Prime, Prime, Razakanaivo, Richter-Trummer, Serizawa, Shan, Shilbi, Sireesha, Sulaiman, Taniguchi, Toparli, Urevc, Wimpory, Xie, Yaghi, Zhang, Zondi.   +30 more
core   +3 more sources