Results 81 to 90 of about 929,788 (310)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Experimental Comparison of R245fa Falling Film Evaporation in Two Doubly-enhanced Tubes
Zhileng xuebao, 2019 The heat transfer performance of two types of doubly enhanced tubes was experimentally studied using R245fa after the horizontal single-tube falling film evaporating test bench was built.
Zhao Jiapu +3 more
doaj
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Zhileng xuebao, 2012 Heat exchangers including condenser and evaporator are important equipments in the compression type refrigeration and air conditioning units, and their heat transfer coefficients have a direct effect on the efficiency and cost of the units.
Zhang Zhengguo +4 more
doaj
Energies, 2019 This study numerically examines the effect of actual gas turbine operating conditions on heat transfer characteristics in a ribbed passage with mist/steam cooling.
Jianying Gong +4 more
doaj +1 more source
Heat transfer characteristics of hydrid microjet-microchannel cooling module [PDF]
, 2014 This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014) +2 more
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Assessing the use of PEC and jf methods for strengthening the evaluation of new heat exchangers
HeliyonThe new type of heat exchanger uses the micro heat pipe as the main heat transfer material. Compared with the traditional heat exchanger of the same kind, the performance of the new type of heat exchanger has significantly improved.
Jingang Yang, Zitong Feng
doaj +1 more source
What’s a Federalist to Do? The Impending Clash Between Textualism and Federalism in State Congressional Redistricting Suits Under Article 1, Section 4 [PDF]
, 2004 Nanofluids (NFs) are nanotechnology-based colloidal dispersion prepared by dispersing nanoparticles (NPs) in conventional liquids, as the base liquid. These advanced fluids have displayed potential to enhance the performance of conventional heat transfer
Wilson, C. Bryan
core +1 more source