Results 71 to 80 of about 2,351,400 (277)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Control of gas-dynamic conditions of cupola process
Литьë и металлургия, 2003 .
I. A. Potapnev, I. I. Bolmatenkova
doaj
Alfvenic Heating of Protostellar Accretion Disks
, 1999 We investigate the effects of heating generated by damping of Alfven waves on protostellar accretion disks. Two mechanisms of damping are investigated, nonlinear and turbulent, which were previously studied in stellar winds (Jatenco-Pereira & Opher 1989a,
Chandrasekhar S. +10 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Method of carbon monoxide elimination during cupola furnace process
Литьë и металлургия, 2001 The work is of interest to the enterprises operating open type cupola. The suggested method of afterburning ensures reduction of CO level below maximum permissible concentration.
S. F. Lukashevich, I. A. Potapnev
doaj
An estimation of exergy consumption paterns of energyâ€intensive building service systems
Journal of Civil Engineering and Management, 2006 This paper represents the estimation of life cycle exergy consumption for building service systems (BSS). The investigation explores public building engineering systems, which are the most energyâ€intensive.
Darius Biekša +2 more
doaj +1 more source
Three Dimensional Structure and Energy Balance of a Coronal Mass Ejection
, 2008 The Ultraviolet Coronagraph Spectrometer (UVCS) observed Doppler shifted material of a partial Halo Coronal Mass Ejection (CME) on December 13 2001. The observed ratio of [O V]/O V] is a reliable density diagnostic important for assessing the state of ...
Akmal +22 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The nomographic charts for calculation and adjustment of mixture at melting of cast iron in cupolas
Литьë и металлургия, 2003 There are offered nomographic charts for calculation and adjustment of mixture at casting of gray and white cast iron in cupola furnaces. The nomographic charts allow to reduce calculations of mixtures, to facilitate the receiving of the intended ...
L. Z. Pisarenko +2 more
doaj
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source