Results 21 to 30 of about 4,061,678 (356)

Gamma heavy chain disease associated with T-cell large granular lymphocyte lymphoproliferative disorder: case report and literature review.

Mediterranean Journal of Hematology and Infectious Diseases, 2023
Heavy chain diseases are rare B-cell neoplasms consisting of the production of a monoclonal immunoglobulin composed of the only heavy chain without corresponding light chains.
Maria Laura Bisegna, Maria Assunta Limongiello, Stefano Fiori, Maria Stefania De Propris, Irene Della Starza, Stefania Trasarti   +5 more
doaj   +1 more source

A simple way to increase recovery of the expressed VH and VL genes in single-sorted human B cells

BioTechniques, 2019
Cloning VH and VL genes from individual antigen-specific B cells is an attractive approach for producing monoclonal antibodies of the desired specificity.
Sergey V Guselnikov, Tatyana N Belovezhets, Sergey V Kulemzin, Andrey A Gorchakov, Alexander V Taranin   +4 more
doaj   +1 more source

Gamma-heavy chain disease

Klinicka Onkologie, 2020
Gamma-heavy chain disease is a rare disease, described so far in approximately 150 cases. The aim of this work was laboratory dia-gnostics of immunoglobulin heavy chain disease.A 60-year-old patient was referred to the University Hospital in Ostrava for suspected marginal zone lymphoma from gastric bio-psy.
P, Kušnierová, D, Zeman, T, Jelínek, R, Hájek   +3 more
openaire   +2 more sources

Lead Toxicity: Health Hazards, Influence on Food Chain, and Sustainable Remediation Approaches

International Journal of Environmental Research and Public Health, 2020
Lead (Pb) toxicity has been a subject of interest for environmental scientists due to its toxic effect on plants, animals, and humans. An increase in several Pb related industrial activities and use of Pb containing products such as agrochemicals, oil ...
Ajay Kumar, Ajay Kumar, Cabral-Pinto M.M.S., A. Chaturvedi, A. Shabnam, G. Subrahmanyam, Raju Mondal, D. Gupta, S. K. Malyan, Smita S. Kumar, Shakeel A. Khan, K. Yadav   +11 more
semanticscholar   +1 more source

Differences in human IgG1 and IgG4 S228P monoclonal antibodies viscosity and self-interactions: Experimental assessment and computational predictions of domain interactions

mAbs, 2021
Human/humanized IgG4 antibodies have reduced effector function relative to IgG1 antibodies, which is desirable for certain therapeutic purposes. However, the developability and biophysical properties for IgG4 antibodies are not well understood. This work
Pin-Kuang Lai, Gaurav Ghag, Yao Yu, Veronica Juan, Laurence Fayadat-Dilman, Bernhardt L. Trout   +5 more
doaj   +1 more source

Vibration of a Flexible Hanging Chain with a Mass on the End in a Nonstationary Regime of the Motion Mechanism in Hoisting Machines [PDF]

Journal of Applied and Computational Mechanics
The article is focused on the vibrations of a heavy chain with a mass on the end when the hoisting machines are in a nonstationary regime of motion, assuming that motor or brake torque is a linear function of the speed of the motion mechanism.
Vassil Zlatanov, Svetoslav Nikolov
doaj   +1 more source

Light and heavy chain deposition disease with focal amyloid deposition diagnosed with mass spectrometry: a case report

BMC Nephrology, 2023
Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys.
Yuki Shimamoto, Naoki Takahashi, Nagaaki Katoh, Yuki Matsui, Yusuke Mochizuki, Masanori Ito, Masahide Yazaki, Fuyuki Kametani, Kenji Kasuno, Yoshiki Sekijima, Hironobu Naiki, Masayuki Iwano   +11 more
doaj   +1 more source

Bariatric Surgery for a Patient With Myosin Heavy Chain 9-Related Disorders (MYH9RD): A Case Report. [PDF]

J Metab Bariatr Surg
Kim SH, Park K, Kim C, Kim J, Kong SH, Lee HJ, Yang HK, Park DJ.   +7 more
europepmc   +3 more sources

Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

Frontiers in Immunology, 2018
Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjögren’s syndrome (pSS) patients. In
Annie Visser, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Marieke E. Doorenspleet, Niek de Vries, Niek de Vries, Fred K. L. Spijkervet, Arjan Vissink, Richard J. Bende, Hendrika Bootsma, Frans G. M. Kroese, Nicolaas A. Bos   +11 more
doaj   +1 more source

Analysis of monoclonal immunoglobulins from bone marrow plasma cells using immunopurification and LC-MS

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023
Introduction: Clonal plasma cells secrete immunoglobulins, each with the exact same amino acid sequence, that are referred to as monoclonal immunoglobulins.
David R. Barnidge, Angela Dispenzieri, Dragan Jevremovic, David L. Murray   +3 more
doaj   +1 more source