Results 21 to 30 of about 398,844 (320)
A simple way to increase recovery of the expressed VH and VL genes in single-sorted human B cells
BioTechniques, 2019 Cloning VH and VL genes from individual antigen-specific B cells is an attractive approach for producing monoclonal antibodies of the desired specificity.
Sergey V Guselnikov +4 more
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Flatness of heavy chain systems [PDF]
Proceedings of the 41st IEEE Conference on Decision and Control, 2002., 2001 This paper gives an overview of the results of Petit and Rouchon (2001). Furthermore it contains some previously unpublished material concerning the homogeneous chain carrying a load. In the above paper the flatness of heavy chain systems, i.e. trolleys carrying a fixed length heavy chain that may carry a load, is addressed in the partial derivatives ...
Pierre Rouchon, Nicolas Petit
openaire +2 more sources
mAbs, 2021 Human/humanized IgG4 antibodies have reduced effector function relative to IgG1 antibodies, which is desirable for certain therapeutic purposes. However, the developability and biophysical properties for IgG4 antibodies are not well understood. This work
Pin-Kuang Lai +5 more
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Non-Gaussian polymers described by alpha-stable chain statistics: model, applications and effective interactions in binary mixtures [PDF]
Phys. Rev. E, 91, 5, 052602 (2015), 2015 The Gaussian chain model is the classical description of a polymeric chain, which provides the analytical results regarding end-to-end distance, the distribution of segments around the mass center of a chain, coarse grained interactions between two chains and effective interactions in binary mixtures.
arxiv +1 more source
Search for large topological gaps in atomic spin chains on proximitized superconducting heavy metal layers [PDF]
Communications Physics 6, 83 (2023), 2023 One-dimensional systems comprising s-wave superconductivity with meticulously tuned magnetism and spin-orbit coupling can realize topologically gapped superconductors hosting Majorana edge modes whose stability is determined by the gap's size. The ongoing quest for larger topological gaps evolved into a material science issue.
arxiv +1 more source
Frontiers in Immunology, 2018 Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjögren’s syndrome (pSS) patients. In
Annie Visser +11 more
doaj +1 more source
BMC Nephrology, 2023 Background Light and heavy chain deposition disease (LHCDD) is a rare condition characterised by the deposition of immunoglobulin components in the kidneys.
Yuki Shimamoto +11 more
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Klinicka Onkologie, 2020 Gamma-heavy chain disease is a rare disease, described so far in approximately 150 cases. The aim of this work was laboratory dia-gnostics of immunoglobulin heavy chain disease.A 60-year-old patient was referred to the University Hospital in Ostrava for suspected marginal zone lymphoma from gastric bio-psy.
Tomas Jelinek +3 more
openaire +2 more sources
Vibration of a Flexible Hanging Chain with a Mass on the End in a Nonstationary Regime of the Motion Mechanism in Hoisting Machines [PDF]
Journal of Applied and Computational MechanicsThe article is focused on the vibrations of a heavy chain with a mass on the end when the hoisting machines are in a nonstationary regime of motion, assuming that motor or brake torque is a linear function of the speed of the motion mechanism.
Vassil Zlatanov, Svetoslav Nikolov
doaj +1 more source
Antibodies, 2020 We report the novel crystal structure and characterization of symmetrical, homodimeric humanized heavy-chain-only antibodies or dimers (HC2s). HC2s were found to be significantly coexpressed and secreted along with mAbs from transient CHO HC/LC ...
Carl Mieczkowski +9 more
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