Results 131 to 140 of about 8,581 (234)

Macro- and Micro-scale Dose Simulation of Heavy Ion Relative Biological Effectiveness

open access: yesYuanzineng kexue jishu
Heavy ion therapy is an important cancer treatment. Accurate evaluation of the biophysical effects of heavy ions is of great significance to improve the refinement level of particle radiotherapy.
HU Ziyi1,2, QIU Rui1,2, CHEN Yizheng4, HU Ankang1,2, WU Zhen1,3, ZHANG Hui1,2, LI Junli1,2
doaj   +1 more source

Recent progress and future plan of heavy-ion cancer radiotherapy with HIMAC

open access: yes, 2016
The HIMAC clinical study has been conducted with a carbon-ion beam since June 1994. The total number of patients treated was around 10,000 as of March 2016.
649395   +3 more
core  

Feasibility Study of Combined Systemic Therapy and Carbon‐Ion Radiotherapy for Hepatocellular Carcinoma Patients

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Recent advances in systemic therapy, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), have improved outcomes for hepatocellular carcinoma (HCC) and enabled downstaging strategies that allow subsequent local treatments. Carbon‐ion radiotherapy (CIRT) can provide excellent tumor control with minimal
Daijiro Kobayashi   +6 more
wiley   +1 more source

Evaluation of base materials of TL slab Dosimeter for heavy-ion radiotherapy

open access: yes, 2013
In order to measure a three-dimensional dose distribution in X-ray radiotherapy, we developed TL slab dosimeter with new TL phosphor Li3B7O12(Cu), which has Zeff = 7.42 and a density of 1.01 g/cm3 and synthetic resin as binder.
玉津, 早駿   +19 more
core  

A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels   +19 more
wiley   +1 more source

Results of heavy ion radiotherapy

open access: yes, 1994
The potential of heavy ion therapy for clinical use in cancer therapy stems from the biological parameters of heavy charged particles, and their precise dose localization.
Castro, J. R.
core  

Vitamin D Pretreatment to Prevent the Risk of Postoperative Hypocalcemic Complications After Parathyroidectomy in Primary Hyperparathyroidism: A Systematic Review and Meta‐Analysis

open access: yesHead &Neck, Volume 48, Issue 7, Page 1865-1875, July 2026.
ABSTRACT Background Parathyroidectomy is the treatment for primary hyperparathyroidism, yet postoperative hypocalcemia and hungry bone syndrome remain common. Vitamin D deficiency has been suggested as a modifiable risk factor, but evidence supporting preoperative supplementation is inconsistent.
Matthew Gynn   +2 more
wiley   +1 more source

Carbon ion radiotherapy at NIRS

open access: yes, 2013
In 1994, carbon ion radiotherapy was begun at the National Institute of Radiological Sciences using the Heavy Ion Medical Accelerator in Chiba, which was the worlds 􀂿rst heavy ion accelerator complex dedicated to medical use in a hospital ...
Kamada, Tadashi   +3 more
core  

Study of prompt gamma and neutron emission for real‐time range verification in proton and carbon‐ion therapy

open access: yesMedical Physics, Volume 53, Issue 7, July 2026.
Abstract Background Accurate range verification is crucial in hadrontherapy to fully exploit the ballistic advantages of charged particles and prevent damage to healthy tissues. Among the proposed approaches, prompt gamma imaging (PGI) has emerged as an effective technique for real‐time monitoring, but its performance is limited by the intense neutron ...
Emma Sofia Bellotti   +6 more
wiley   +1 more source

Development and evaluation of an in vivo dose‐based monitoring system for electron FLASH radiation therapy

open access: yesMedical Physics, Volume 53, Issue 7, July 2026.
Abstract Background FLASH radiotherapy requires further preclinical and clinical investigation to establish its biological effectiveness and define optimal beam parameters. In conventional (CONV) radiotherapy, redundant beam termination systems are a cornerstone ensuring patient safety, yet analogous safeguards for FLASH delivery are not well ...
Justin DeFrancisco   +5 more
wiley   +1 more source

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