Results 131 to 140 of about 7,859 (235)

Machine Learning‐Based Profiling of Urinary Volatile Organic Compounds Reveals Distinct Diagnostic Signatures for Gastric Cancer

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Introduction Gastric cancer (GC) is a leading cause of cancer‐related mortality worldwide, often diagnosed at advanced stages due to the absence of specific symptoms. This study aimed to explore the potential of urinary volatile organic compounds (VOCs) as non‐invasive biomarkers for gastric cancer diagnosis.
Tao Sha, Wenyan Fei, Yun Zhao, Lin Bai
wiley   +1 more source

Development of plant‐derived biomimetic nanoparticles as a novel targeted drug delivery platform

open access: yesClinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Plant‐derived biomimetic nanoparticles (PD‐BNPs) represent a sustainable and biocompatible nanoplatform for targeted drug delivery. This review highlights their therapeutic potential, engineering strategies, and translational challenges toward precision nanomedicine applications. Abstract Plant‐derived biomimetic nanoparticles (PD‐BNPs) have emerged as
Jihad Hasan   +3 more
wiley   +1 more source

Neutrophil‐based immunotherapy: A metabolic lens on mechanisms and therapeutic implications

open access: yesClinical and Translational Medicine, Volume 16, Issue 8, August 2026.
TAN metabolic reprogramming critically contributes to tumour immune evasion. A 4‑Tier TAN‑MetaC classification framework is proposed, along with an overview of translational opportunities and bottlenecks for TAN metabolism‑targeted immunotherapies. Abstract Background Tumor‐associated neutrophils (TANs) serve as pivotal immune modulators in the tumor ...
Wenchao Xu   +4 more
wiley   +1 more source

Quantum scalpel project for advanced heavy-ion radiotherapy

open access: yesQuantum scalpel project for advanced heavy-ion radiotherapy
Quantum scalpel project for advanced heavy-ion radiotherapy K. Noda1 1 National Institute of Radiological Sciences, QST, Chiba, Chiba, Japan \nContent The HIMAC clinical study has been conducted with a carbon-ion beam since June 1994. The total number of patients treated as of 2017 was in excess of 10,000.
openaire   +1 more source

SARS‐CoV‐2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways

open access: yesEuropean Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Pain is a common neurological manifestation of COVID‐19, yet the mechanisms by which SARS‐CoV‐2 spike protein fragments contribute to nociceptive processing remain poorly understood. We investigated whether spike‐derived peptides directly activate spinal neuroimmune pathways involved in pain signalling.
Bruno Eduardo Silva   +15 more
wiley   +1 more source

Advancing Tumor Treatment Through Artificial Intelligence and Mathematical Modeling: A Comprehensive Review

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Solid tumors emerge from uncontrolled cell division and interactions with neighboring cells that influence their growth and resistance to therapy. Anti‐cancer drugs are developed to disrupt these processes, but they often damage healthy cells, making treatment difficult to manage safely and effectively. As the global cancer
Mohsin Kamran   +3 more
wiley   +1 more source

Corrigendum: A comparative study of two in vivo PET verification methods in clinical cases

open access: yesFrontiers in Oncology
Junyu Zhang   +24 more
doaj   +1 more source

Review on heavy ion radiotherapy facilities and related ion sources

open access: yesReview on heavy ion radiotherapy facilities and related ion sources
Heavy ion radiotherapy awakens worldwide interest recently. The clinical results obtained by the Heavy Ion Medical Accelerator in Chiba at the National Institute of Radiological Sciences in Japan have clearly demonstrated the advantages of carbon ion radiotherapy. Presently, there are four facilities for heavy ion radiotherapy in operation, and several
openaire  

Paeonol as a Multi‐Target Therapy for Neurological Disorders: Mechanistic Insights Into Neuroprotection

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
Paeonol (PNL) exhibits neuroprotective effects by reducing oxidative stress, neuroinflammation, and apoptosis. It enhances antioxidant defenses (SOD and GSH), inhibits pro‐inflammatory pathways (NF‐κB and TLR4), and modulates apoptotic proteins (Bcl‐2 and Bax).
Md. Sakib Al Hasan   +9 more
wiley   +1 more source

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