Results 121 to 130 of about 8,581 (234)

Junctional Adhesion Molecule‐A (JAM‐A) Associates With High‐Risk Disease in Multiple Myeloma Patients and a Structure‐Based Rationally‐Designed Peptide Inhibitor Attenuates Tumorigenic Features In Vitro and In Vivo

European Journal of Haematology, EarlyView.
ABSTRACT Multiple myeloma (MM) is an incurable malignancy of terminally‐differentiated plasma cells that represents a major clinical challenge despite unprecedented therapeutic advances, particularly for patients with cytogenetically‐defined high‐risk MM (HR‐MM).
Niamh McAuley, Roisin McAvera, Dimitri Bong, Lara Donnelly, Izabela Cymer, Marian Brennan, Joanna Fay, Lance Hudson, John Quinn, Siobhan V. Glavey, Ann M. Hopkins   +10 more
wiley   +1 more source

Neurovascular Disorders in Pregnancy: Prevalence, Clinical Assessment and Management—A Review of the Literature

The Obstetrician &Gynaecologist, EarlyView.
ABSTRACT Key Content Neurovascular conditions in pregnancy are rare but are associated with poor maternal and fetal outcomes. This review covers the prevalence, clinical presentation, diagnosis and management of neurovascular disorders in pregnancy. The approach to clinical assessment and investigation of pregnant women with acute or changing chronic ...
Amy Newnham, Joshua Odendaal, Toby Keown, Wen‐Xern Chong, Krunal Patel, Vandana Dhingra   +5 more
wiley   +1 more source

Optimization of treatment planning for hypoxic tumours and re-modulation of radiation intensity in heavy-ion radiotherapy. [PDF]

Rep Pract Oncol Radiother, 2020
Rezaee L.
europepmc   +1 more source

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube, Donald Fernandes, Arthur Abinader Vasconcelos, Hugo de Campos Braga, Alan Kelbis Oliveira Lima, José Arnaldo Santana Costa, Karla Furtado Andriani, Ester da Cunha Meira Santos, Antonio Jorge Silva Araújo Junior, Hauster Maximiler Campos de Paula, Wallace Júnio Reis, Kashif Gul, Nida Wahab, Luis Carlos Resio, Elisa Kawana Leal dos Santos, Márcio Peres de Araujo, Matheus Allen P. da Silva, Juliana Paula da Silva   +17 more
wiley   +1 more source

The Importance and Clinical Implications of FLASH Ultra-High Dose-Rate Studies for Proton and Heavy Ion Radiotherapy. [PDF]

Radiat Res, 2020
Colangelo NW, Azzam EI.
europepmc   +1 more source

Biomimetic Polymerization of Tellurocysteine: Breaking the Natural Amino Acid Radioprotection Limitation

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Inspired by natural amino acid polymer‐melanin systems, this study strategically incorporated tellurocysteine to develop advanced radiation‐shielding materials. This approach transformed the primary interaction mechanism between melanin‐based materials and incident photons from Compton scattering to the photoelectric effect. Tellurocysteine‐polymerized
Wei Chen, Hanjie Zhu, Yue Zhang, Yuqing Qiao, Ruotong Deng, Huaping Xu, Wei Cao   +6 more
wiley   +1 more source

Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis

Journal of Translational Medicine
Background Photon radiation has been shown to stimulate the secretion of radioresistant factors from tumor cells, ultimately promoting tumor angiogenesis and metastasis.
Hao Huang, Ying Xu, Zi Guo, Miaomiao Zhang, Wanshi Li, Yidan Song, Jing Nie, Wentao Hu, Tom K. Hei, Guangming Zhou   +9 more
doaj   +1 more source

Heavy ion therapy: Bevalac epoch [PDF]

, 1993
An overview of heavy ion therapy at the Bevelac complex (SuperHILac linear accelerator + Bevatron) is given. Treatment planning, clinical results with helium ions on the skull base and uveal melanoma, clinical results with high-LET charged particles ...
Castro, J. R., Castro, J.R., Castro, J R
core  

Damaging Intermolecular Relaxation Processes Initiated by Heavy-Ion Irradiation of Hydrated Biomolecules

Physical Review X
Intermolecular Coulombic decay (ICD) is considered a general phenomenon that plays a key role in many fundamental and applied fields related to biological environments. In many cases, however, the mechanisms and efficiency of ICD have yet to be uncovered.
Yue Gao, Anna D. Skitnevskaya, Enliang Wang, Hang Yuan, Xueguang Ren, Hong Lin, Zhenyu Yan, Shaofeng Zhang, Shaofei Gu, Bo Yang, Feng Fang, Shuncheng Yan, Dalong Guo, Xiaolong Zhu, Dongmei Zhao, Caojie Shao, Zhongkui Huang, Xiaorui Xue, Xintai Hao, Jiaqi Zhou, Tongmin Zhang, Jinyu Li, Xinliang Yan, Meng Wang, Lijun Mao, Dayu Yin, Meitang Tang, Youjin Yuan, Jiancheng Yang, Alexander B. Trofimov, Lorenz S. Cederbaum, Alexander I. Kuleff, Xinwen Ma, Shenyue Xu   +33 more
doaj   +1 more source

Superior tumor cell killing by oxygen ion beam irradiation compared to carbon ions and photons in pancreatic Cancer cells – An in vitro investigation

Clinical and Translational Radiation Oncology
Pancreatic cancer remains one of the most treatment-refractory malignancies, displaying profound resistance to chemotherapy and radiotherapy. While the benefit of photon radiotherapy remains debated, heavy-ion modalities such as carbon ions show promise ...
Lixin Mai, Aleksei Smirnov, Michael M. Allers, Zhengyang Song, Muzi Liu, Thuy Trinh, Stephan Brons, Fabian Weykamp, Jakob Liermann, Ramon Lopez Perez, Jürgen Debus, Peter E. Huber, Jonathan M. Schneeweiss   +12 more
doaj   +1 more source