Results 101 to 110 of about 8,581 (234)

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

Heavy-ion transport codes for radiotherapy and radioprotection in space

, 2006
Simulation of the transport of heavy ions in matter is a field of nuclear science that has recently received attention in view of its importance for some relevant applications.
Mancusi, Davide,
core   +1 more source

Combination of 99mTc-Labeled PSMA-SPECT/CT and Diffusion-Weighted MRI in the Prediction of Early Response After Carbon Ion Therapy in Prostate Cancer: A Non-Randomized Prospective Pilot Study

Cancer Management and Research, 2021
Ping Li,1– 3,* Chang Liu,4– 6,* Shuang Wu,2,3,7 Lin Deng,2,3,8 Guangyuan Zhang,2,3,8 Xin Cai,1– 3 Silong Hu,4– 6 Jingyi Cheng,2,3,6,9 Xiaoping Xu,4– 6 Bin Wu,2,3,10 Xiaomao Guo,2,3,7 Yingjian Zhang,4– 6 Shen Fu,5,11 ...
Li P, Liu C, Wu S, Deng L, Zhang G, Cai X, Hu S, Cheng J, Xu X, Wu B, Guo X, Zhang Y, Fu S, Zhang Q   +13 more
doaj  

Twenty-Year Development of Heavy-Ion Radiotherapy Technology with HIMAC

, 2015
Heavy-ion beams are very suitable for the treatment of deeply seated cancer because of an excellent physical-dose distribution and high biological effect around the Bragg peak. Heavy-Ion Medical Accelerator in Chiba, HIMAC, therefore, was constructed for
647283, 野田 耕司, Noda, Koji, 647282   +3 more
core  

Non-randomized therapy trial to determine the safety and efficacy of heavy ion radiotherapy in patients with non-resectable osteosarcoma [PDF]

, 2010
Background Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. For effective treatment, local control of the tumor is absolutely critical, because the chances of long term survival are EURAMOS1.
Ewerbeck Volker, Kulozik Andreas E, Claudia Blattmann, Sabine Haufe, Oliver Jäkel, Stefan Rieken, Haufe Sabine, Debus Jürgen, Jäkel Oliver, Volker Ewerbeck, Combs, Stephanie E, Bischof Marc, Haufe, Sabine, Nikoghosyan Anna, Ewerbeck, Volker, Huber, Peter, Debus, Jürgen, Peter Huber, Karapanagiotou-Schenkel Irini, Nikoghosyan, Anna, Stephanie E Combs, Oertel, Susanne, Andreas E Kulozik, Blattmann Claudia, Marc Bischof, Schulz-Ertner Daniela, Unterberg Andreas, Blattmann, Claudia, Combs Stephanie E, Huber Peter, Daniela Schulz-Ertner, Anna Nikoghosyan, Jürgen Debus, Rieken, Stefan, Susanne Oertel, Unterberg, Andreas, Bischof, Marc, Irini Karapanagiotou-Schenkel, Jäkel, Oliver, Kulozik, Andreas E, Andreas Unterberg, Karapanagiotou-Schenkel, Irini, Rieken Stefan, Oertel Susanne, Schulz-Ertner, Daniela   +44 more
core   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng, Ling‐Mei Qu, Jun‐Jie Liu, Yu‐Shan Li, Zi‐Qi Chen, Shuo Liu, Zhao‐Nan Xu, Meng Jin, Qiu‐Ying Li, Qin Wu, Hong‐Tian Yi, Xian‐Ji Shen, Bing‐Rui Yan, Ya‐Nan Sun   +13 more
wiley   +1 more source

A future directions of renal cell carcinoma treatment: combination of immune checkpoint inhibition and carbon ion radiotherapy

Frontiers in Immunology
Renal cell carcinoma (RCC) is considered radio- and chemo-resistant. Immune checkpoint inhibitors (ICIs) have demonstrated significant clinical efficacy in advanced RCC. However, the overall response rate of RCC to monotherapy remains limited.
Zhouhang Zheng, Zhouhang Zheng, Tianci Yang, Tianci Yang, Yixuan Li, Yixuan Li, Pei Qu, Pei Qu, Zhiang Shao, Zhiang Shao, Yuan Wang, Yuan Wang, Wei Chang, Shahzad Muhammad Umar, Jufang Wang, Jufang Wang, Nan Ding, Nan Ding, Wei Wang   +18 more
doaj   +1 more source

Development of an IH-DTL injector for the Heidelberg cancer therapy project

, 2005
Cancer has become one of the most fatal diseases. The Heidelberg Heavy Ion Cancer Therapy (HICAT) has the potential to become an important and efficient treatment method because of its excellent “Bragg peak” characteristics and on-line irradiation ...
Lu, Yuanrong
core  

Design and commissioning of a new synchrotron beamline dedicated to X‐ray footprinting mass spectrometry

Journal of Synchrotron Radiation, EarlyView.
A dedicated beamline at the Advanced Light Source synchrotron has been opened and commissioned for X‐ray footprinting mass spectrometry.The structural biology method of X‐ray footprinting mass spectrometry (XFMS) is available at two national synchrotron beamlines in the USA: one at the Advanced Light Source (ALS) on the West Coast and the other at the ...
Sayan Gupta, Brandon Russell, Line G. Kristensen, Jared de Chant, Anthony Lu, Lieselotte Obst-Huebl, Behzad Rad, James Tyler, Simruthi Subramanian, Savannah Kidd, Sathi Paul, Yan Chen, Christopher J. Petzold, Darren N. Kahan, Shawn M. Costello, Kei Nakamura, Jamie L. Inman, Alastair A. MacDowell, Adrian Spucces, Corie Y. Ralston   +19 more
wiley   +1 more source

Toward Multi(radio)metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates

Angewandte Chemie, Volume 138, Issue 27, 1 July 2026.
This work presents the first enzymatic polymerization of defined metal‐chelator‐modified nucleotides that leverage polymerase fidelity for uniform (radio)metal loading with successful incorporation of five different metals: Ga, In, Tb, Lu, and Y.
Antonio A. W. L. Wong, François Bénard, David M. Perrin   +2 more
wiley   +2 more sources