Results 91 to 100 of about 7,859 (235)

Optimization of treatment planning for hypoxic tumours and re-modulation of radiation intensity in heavy-ion radiotherapy. [PDF]

Rep Pract Oncol Radiother, 2020
Rezaee L.
europepmc   +1 more source

Junctional Adhesion Molecule‐A (JAM‐A) Associates With High‐Risk Disease in Multiple Myeloma Patients and a Structure‐Based Rationally‐Designed Peptide Inhibitor Attenuates Tumorigenic Features In Vitro and In Vivo

European Journal of Haematology, EarlyView.
ABSTRACT Multiple myeloma (MM) is an incurable malignancy of terminally‐differentiated plasma cells that represents a major clinical challenge despite unprecedented therapeutic advances, particularly for patients with cytogenetically‐defined high‐risk MM (HR‐MM).
Niamh McAuley, Roisin McAvera, Dimitri Bong, Lara Donnelly, Izabela Cymer, Marian Brennan, Joanna Fay, Lance Hudson, John Quinn, Siobhan V. Glavey, Ann M. Hopkins   +10 more
wiley   +1 more source

The Importance and Clinical Implications of FLASH Ultra-High Dose-Rate Studies for Proton and Heavy Ion Radiotherapy. [PDF]

Radiat Res, 2020
Colangelo NW, Azzam EI.
europepmc   +1 more source

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

Journal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil M. O'Brien‐Simpson, Vladimir Baulin, Peter Kingshott, Roy Judge, Alastair J. Sloan, Elena P. Ivanova   +9 more
wiley   +1 more source

Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis

Journal of Translational Medicine
Background Photon radiation has been shown to stimulate the secretion of radioresistant factors from tumor cells, ultimately promoting tumor angiogenesis and metastasis.
Hao Huang, Ying Xu, Zi Guo, Miaomiao Zhang, Wanshi Li, Yidan Song, Jing Nie, Wentao Hu, Tom K. Hei, Guangming Zhou   +9 more
doaj   +1 more source

Superior tumor cell killing by oxygen ion beam irradiation compared to carbon ions and photons in pancreatic Cancer cells – An in vitro investigation

Clinical and Translational Radiation Oncology
Pancreatic cancer remains one of the most treatment-refractory malignancies, displaying profound resistance to chemotherapy and radiotherapy. While the benefit of photon radiotherapy remains debated, heavy-ion modalities such as carbon ions show promise ...
Lixin Mai, Aleksei Smirnov, Michael M. Allers, Zhengyang Song, Muzi Liu, Thuy Trinh, Stephan Brons, Fabian Weykamp, Jakob Liermann, Ramon Lopez Perez, Jürgen Debus, Peter E. Huber, Jonathan M. Schneeweiss   +12 more
doaj   +1 more source

Experimental and computational characterisation of the secondary fragment field in clinical proton therapy beams using microdosimetry

Precision Radiation Oncology, EarlyView.
Gabriele Parisi, Marta Missiaggia, Enrico Pierobon, Francesco Cordoni, Enrico Verroi, Claudio Verona, Giuseppe Schettino, Chiara La Tessa   +7 more
wiley   +1 more source

Avian Eggshell Evolutionary Adaptations Inform Biomimetic Strategies for Next‑Generation Precision Cancer Theranostics

Advanced Oncology, Volume 1, Issue 1, December 2026.
ABSTRACT The avian eggshell is a sophisticated, multi‐functional biocomposite and, more importantly, an autonomous life‐support system evolved to safeguard embryonic development across dynamic and hostile environments. Discussing eggshell‐inspired biomaterials beyond simple structural imitation, this review translates these evolutionary survival ...
Zhiqiang Liu, Sida Ling, Mengqi Zhao, Chunyan Zhu, Yaoye Zhou, Hengquan Hou, Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Zuyong Wang, Swee Hin Teoh   +11 more
wiley   +1 more source

Damaging Intermolecular Relaxation Processes Initiated by Heavy-Ion Irradiation of Hydrated Biomolecules

Physical Review X
Intermolecular Coulombic decay (ICD) is considered a general phenomenon that plays a key role in many fundamental and applied fields related to biological environments. In many cases, however, the mechanisms and efficiency of ICD have yet to be uncovered.
Yue Gao, Anna D. Skitnevskaya, Enliang Wang, Hang Yuan, Xueguang Ren, Hong Lin, Zhenyu Yan, Shaofeng Zhang, Shaofei Gu, Bo Yang, Feng Fang, Shuncheng Yan, Dalong Guo, Xiaolong Zhu, Dongmei Zhao, Caojie Shao, Zhongkui Huang, Xiaorui Xue, Xintai Hao, Jiaqi Zhou, Tongmin Zhang, Jinyu Li, Xinliang Yan, Meng Wang, Lijun Mao, Dayu Yin, Meitang Tang, Youjin Yuan, Jiancheng Yang, Alexander B. Trofimov, Lorenz S. Cederbaum, Alexander I. Kuleff, Xinwen Ma, Shenyue Xu   +33 more
doaj   +1 more source

Circulating Tumor DNA and Immune Response Markers for Improved Treatment Outcome Prediction in Diffuse Large B‐Cell Lymphoma: A Scoping Review

Hematological Oncology, Volume 44, Issue 5, September 2026.
ABSTRACT Early identification of refractory disease remains a significant unmet clinical need in patients with diffuse large B‐cell lymphoma (DLBCL). This scoping review was conducted to assess the current knowledge on the use of circulating tumor DNA (ctDNA), either alone or in combination with immune markers, as predictive tools for treatment outcome
Ailin McMahon, Elizabeth J. Ryan, Sarah Dillon, Ruth Clifford   +3 more
wiley   +1 more source