Results 81 to 90 of about 7,859 (235)

Back with Weight: Revisiting Very Heavy Ions for Precision Radiotherapy

Radiation Research
In press on Radiation ...
Jansen, Jeannette, Sokol, Olga, Prezado, Yolanda, Durante, Marco   +3 more
openaire   +3 more sources

Normal tissue complication probability models of late cardiopulmonary toxicity following deep inspiration breath hold for breast cancer adjuvant radiotherapy

Precision Radiation Oncology, EarlyView.
Deep inspiration breath hold (DIBH) markedly cuts heart and left lung radiation doses during left‐sided breast cancer radiotherapy. The normal tissue complication probability (NTCP) model further confirms lower predicted cardiopulmonary toxicities versus free breathing (FB), potentially improving patients’ quality of life.
Lin Lin, Liang Liu, Zhengxin Gao, Yaling Hong, Qing Gong, Zhan Yu, Xue Liu, Qiaoying Hu, Yongqiang Li, Shen Fu, Qi Yu   +10 more
wiley   +1 more source

Immunomodulatory Nanozymes as Programmable Redox–Immune Set‐Point Regulators

Small, EarlyView.
Conceptual phase space linking reactive oxygen species level/dynamics to immune state, with pathological set‐points for chronic inflammation, tumor escape, and degeneration contrasted against a central healthy redox–immune set‐point. Buffering and amplifying nanozymes are depicted as devices that dial redox tone up or down to steer diseased ...
Sumi Choi, Minjeong Kim, Sang Jin Lee, Su‐Hwan Kim   +3 more
wiley   +1 more source

Diverse DTPA‐chelated lanthanides with relevance for nuclear medicine bound to an engineered lipocalin reveal conserved ligand geometry

Acta Crystallographica Section F, EarlyView.
Structural and binding studies of the engineered lipocalin CL31d towards the chelate complexes of 11 different lanthanide and main‐group metal(III) ions, whose radioisotopes are useful for nuclear medicine, with a functionalized DTPA revealed a surprisingly broad tolerance towards varying ionic radii, thus enabling flexible radionuclide‐targeting ...
Alina Mirwald, Andreas Eichinger, Arne Skerra   +2 more
wiley   +1 more source

Physical Modelling of Proton and Heavy Ion Radiation using Geant4

EPJ Web of Conferences, 2012
Protons and heavy ion particles are considered to be ideal particles for use in external beam radiotherapy due to superior properties of the dose distribution that results when these particles are incident externally and due to their relative biological ...
Douglass M., Bezak E.
doaj   +1 more source

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Pencil Beam Scanning Carbon Ion Radiotherapy for Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2023
Wenna Zhang,1– 3 Xin Cai,1– 3 Jiayao Sun,2– 4 Weiwei Wang,2– 4 Jingfang Zhao,2– 4 Qing Zhang,1– 3 Guoliang Jiang,1– 3,5 Zheng Wang1– 3,5 1Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, People’s Republic of China ...
Zhang W, Cai X, Sun J, Wang W, Zhao J, Zhang Q, Jiang G, Wang Z   +7 more
doaj  

Transporter‐Associated Therapeutic Efficacy of an SMVT‐Targeted Boron Carrier in Boron Neutron Capture Therapy

Cancer Science, EarlyView.
The transporter‐associated BNCT strategy using BBCIP with or without BPA according to tumor transporter characteristics. BPA showed greater efficacy in LAT1‐dominant F98 glioma, whereas BBCIP was more effective in SMVT‐high CRL1666 tumors, suggesting the potential utility of transporter‐based boron carrier selection in BNCT.
Kenichiro Eza, Kohei Tsujino, Rina Shidoh‐Kazuki, Yoshiki Fujikawa, Hideki Kashiwagi, Gen Futamura, Ryo Hiramatsu, Toshihiro Takami, Masahiko Wanibuchi, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Kai Nishimura, Shota Tanaka, Hiroyuki Nakamura, Shinji Kawabata   +15 more
wiley   +1 more source

ABSTRACTS

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Precision Radiation Oncology, EarlyView.
wiley   +2 more sources

High Uric Acid Promotes Stem Leydig Cell Senescence by CCDC90B Mediates Mitochondrial Quality Control Imbalance

Cell Proliferation, EarlyView.
In hyperuricemia, uric acid inhibits CCDC90B ubiquitination degradation by binding to it. Excessive CCDC90B induces mitochondrial calcium overload, leading to mitochondrial quality control imbalance and ultimately resulting in SLC senescence and decreased testosterone levels.
Jiayu Huang, Ao Wang, Xiangyu Li, Peng Huang, Kaixuan Zeng, Lu Sun, Moxuan Li, Yixiang Chen, Jiancheng Wang   +8 more
wiley   +1 more source