Results 21 to 30 of about 20,916 (244)

The Emerging Potential of Multi-Ion Radiotherapy

Frontiers in Oncology, 2021
Research into high linear energy transfer (LET) radiotherapy now spans over half a century, beginning with helium and deuteron treatment in 1952 and today ranging from fast neutrons to carbon-ions.
Daniel K. Ebner, Steven J. Frank, Taku Inaniwa, Shigeru Yamada, Toshiyuki Shirai   +4 more
doaj   +1 more source

National Effort to Re-Establish Heavy Ion Cancer Therapy in the United States

Frontiers in Oncology, 2022
In this review, we attempt to make a case for the establishment of a limited number of heavy ion cancer research and treatment facilities in the United States.
Arnold Pompos, Robert L. Foote, Albert C. Koong, Quynh Thu Le, Radhe Mohan, Harald Paganetti, Hak Choy   +6 more
doaj   +1 more source

Modulation of gene expression in endothelial cells in response to high LET nickel ion irradiation [PDF]

, 2014
Ionizing radiation can elicit harmful effects on the cardiovascular system at high doses. Endothelial cells are critical targets in radiation-induced cardiovascular damage.
Aerts, An, Baatout, Sarah, Beck, Michaël, De Vos, Winnok, Dieriks, Birger, Ernst, Eric, Janssen, Ann, Lambert, Charles, Lee, Ryonfa, Michaux, Arlette, Moreels, Marjan, Neefs, Mieke, Quintens, Roel, Rombouts, Charlotte, Tabury, Kevin, Van Oostveldt, Patric   +15 more
core   +1 more source

Efficacy and Safety of 4 Fractions of Carbon-Ion Radiation Therapy for Hepatocellular Carcinoma: A Prospective Study

Liver Cancer, 2021
Introduction: Prospective evidence supporting the safety and efficacy of carbon-ion radiotherapy (C-ion RT) for hepatocellular carcinoma (HCC) remains lacking.
Kei Shibuya, Hiroyuki Katoh, Yoshinori Koyama, Shintaro Shiba, Masahiko Okamoto, Shohei Okazaki, Kenichiro Araki, Satoru Kakizaki, Ken Shirabe, Tatsuya Ohno   +9 more
doaj   +1 more source

Basics of Radiation Biology When Treating Hyperproliferative Benign Diseases

Frontiers in Immunology, 2017
For decades, low- and moderate-dose radiation therapy (RT) has been shown to exert a beneficial therapeutic effect in a multitude of non-malignant conditions including painful degenerative muscoloskeletal and hyperproliferative disorders.
Franz Rödel, Claudia Fournier, Julia Wiedemann, Felicitas Merz, Udo S. Gaipl, Benjamin Frey, Ludwig Keilholz, M. Heinrich Seegenschmiedt, Claus Rödel, Stephanie Hehlgans   +9 more
doaj   +1 more source

Evaluation of X-ray and carbon-ion beam irradiation with chemotherapy for the treatment of cervical adenocarcinoma cells in 2D and 3D cultures

Cancer Cell International, 2022
Background Cervical cancer is the second most common cancer in women and causes more than 250,000 deaths worldwide. Among these, the incidence of cervical adenocarcinomas is increasing.
Kazumasa Sekihara, Hidetomo Himuro, Nao Saito, Yukihide Ota, Taku Kouro, Yohsuke Kusano, Shinichi Minohara, Ryoichi Hirayama, Hiroyuki Katoh, Tetsuro Sasada, Daisuke Hoshino   +10 more
doaj   +1 more source

Measurement and Protection of Induced Radioactivity in Proton Heavy Ion Accelerator Therapy

Journal of Isotopes, 2021
Proton-heavy ion therapy is internationally recognized as the most advantageous radiotherapy method in oncology. However, due to the relatively high energy of the proton-heavy ion beams, the secondary neutrons produced in the process of beam energy loss ...
HU Qisheng;YANG Jun
doaj   +1 more source

Carbon Ion Therapy: A Modern Review of an Emerging Technology

Frontiers in Oncology, 2020
Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By
Timothy D. Malouff, Anita Mahajan, Sunil Krishnan, Chris Beltran, Danushka S. Seneviratne, Daniel Michael Trifiletti   +5 more
doaj   +1 more source

Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]

, 2018
The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski, Anna Brożyna, Anna Markiewicz, Bożena Romanowska-Dixon, Ewa Podgórska, Krystyna Urbańska, Martyna Elas, Martyna Śniegocka, Małgorzata Szczygieł, Michał Żmijewski, Mirosława Cichorek, Przemysław Płonka   +11 more
core   +1 more source

Maxillo-mandibular osteoradionecrosis following C-ion radiotherapy: Clinical notes and review of literature

European Journal of Inflammation, 2020
Osteoradionecrosis (ORN) is one of the most feared complications after head and neck radiotherapy. Among head and neck sites, the mandible is the most commonly involved bone.
Valeria Dell’Era, Paolo Aluffi Valletti, Giacomo Garzaro, Massimiliano Garzaro   +3 more
doaj   +1 more source