Results 41 to 50 of about 65,792 (310)

STUDY OF THE INFLUENCE OF THE PASSAGE OF HEAVY TRAINS ON THE THROUGHPUT AND CARRYING CAPACITY OF RAILWAY SECTIONS WITH ELECTRIC TRAIN TRACTION

open access: yesInternational Journal of Advanced Studies, 2022
The criterion for the effectiveness of the organization of heavy traffic on the sections of the Russian railway network is the presence of large correspondences of bulk goods presented by the consignor for transportation.
Valentina V. Shirokova   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Characteristic dynamic traffic load effects in bridges

open access: yes, 2009
When formulating an approach to assess bridge traffic loading with allowance for Vehicle-Bridge Interaction (VBI), a trade-off is necessary between the limited accuracy and computational demands of numerical models and the limited time periods for which ...
O\u27Brien, Eugene J.   +10 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

A study of self-similar traffic generation for ATM networks [PDF]

open access: yes, 1997
This thesis discusses the efficient and accurate generation of self-similar traffic for ATM networks. ATM networks have been developed to carry multiple service categories.
Chen, Hung-Ming, Chen, H.
core  

Passenger Car Equivalents for Heavy Vehicles at Roundabouts. a Synthesis Review

open access: yesFrontiers in Built Environment, 2019
Passenger Car Equivalents (PCEs in the following) are used to transform a mixed fleet of vehicles into a fleet of equivalent passenger cars and to analyze capacity and level-of-service of roads and intersections.
Orazio Giuffrè   +4 more
doaj   +1 more source

On Priority Queues in Heavy Traffic

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1970
Summary For single-server, first-come-first-served queues, specified completely by the sequences of interarrival times and service times, if these sequences are stationary and if (in some sense) there is not too much dependence within or between them, it has been shown by Kingman (1962) that the waiting-time distribution is, in heavy ...
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Correlation between vehicular traffic and heavy metal concentrations in road sediments of Bogotá, Colombia

open access: yesRevista de la Facultad de Medicina, 2019
Introduction: Diseases such as asthma and lung cancer are associated with heavy traffic in urban areas. A deep understanding of the pollutants generated by road traffic is relevant to public health control.
Carlos Zafra-Mejía   +2 more
doaj   +1 more source

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