Results 51 to 60 of about 65,792 (310)

Heavy Traffic Analysis of Polling Systems in Tandem [PDF]

open access: yesOperations Research, 1999
We analyze the performance of a tandem queueing network populated by two customer types. The interarrival times of each type and the service times of each type at each station are independent random variables with general distributions, but the load on each station is assumed to be identical.
Martin I. Reiman, Lawrence M. Wein
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Traffic Data Platform based on the Service Oriented Architecture (SOA) [PDF]

open access: yes, 2010
The DLR Traffic Data Platform (TDP) that is currently being developed by the German Aerospace Center (DLR) is an autonomous decentralised ITS system for distributed intelligent traffic data management and dissemination.
Brockfeld, Elmar   +5 more
core  

Peculiarities of metal work in the defect formation zone of a monoblock crossing

open access: yesВестник Научно-исследовательского института железнодорожного транспорта
Introduction. The paper analyses the causes of appearance and development of defects of the solid block with wing rails and welded rail ends (monoblock crossing) operating under heavy and intensive traffic conditions.
P. V. Tregubchak
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Traffic, diesel and asthma : a literature review [PDF]

open access: yes, 2007
This article details the major pollutants from motor vehicle exhaust, mainly particulate matter, nitrogen dioxide and polycyclic aromatic hydrocarbons.
Schembri, Gabriel
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Assessment dynamic ratio for traffic loading on highway bridges

open access: yes, 2011
The determination of characteristic bridge load effect is a complex problem. Usually, statistical extrapolation of simulated static load effects is used to derive a lifetime characteristic static load effect.
O\u27Brien, Eugene J.   +4 more
core   +1 more source

Self-Reported Truck Traffic on the Street of Residence and Symptoms of Asthma and Allergic Disease: A Global Relationship in ISAAC Phase 3 [PDF]

open access: yes, 2009
BACKGROUND: Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries ...
H. Ross Anderson   +20 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy