Results 51 to 60 of about 584,932 (288)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Asymptotic optimality of maximum pressure policies in stochastic processing networks

open access: yes, 2008
We consider a class of stochastic processing networks. Assume that the networks satisfy a complete resource pooling condition. We prove that each maximum pressure policy asymptotically minimizes the workload process in a stochastic processing network in ...
Dai, J. G., Lin, Wuqin
core   +2 more sources

Diffusion approximation for a processor sharing queue in heavy traffic [PDF]

open access: yes, 2004
Consider a single server queue with renewal arrivals and i.i.d. service times in which the server operates under a processor sharing service discipline.
Gromoll, H. Christian
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Heavy Vehicle Performance During Recovery From Forced-Flow Urban Freeway Conditions Due To Incidents, Work Zones and Recurring Congestion [PDF]

open access: yes, 2013
Information contained in the Highway Capacity Manual on the influence heavy vehicles have on freeway traffic operations has been based on few field data collection efforts and relied mostly on traffic simulation efforts.
Drakopoulos, Alexander   +2 more
core   +1 more source

On many-server queues in heavy traffic

open access: yes, 2010
We establish a heavy-traffic limit theorem on convergence in distribution for the number of customers in a many-server queue when the number of servers tends to infinity. No critical loading condition is assumed.
Puhalskii, Anatolii A., Reed, Josh E.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Passenger Car Equivalents for Heavy Vehicles at Roundabouts. a Synthesis Review

open access: yesFrontiers in Built Environment, 2019
Passenger Car Equivalents (PCEs in the following) are used to transform a mixed fleet of vehicles into a fleet of equivalent passenger cars and to analyze capacity and level-of-service of roads and intersections.
Orazio Giuffrè   +4 more
doaj   +1 more source

Erratum: “Transform Methods for Heavy-Traffic Analysis”

open access: yesStochastic Systems, 2022
In Hurtado-Lange and Maguluri (2020) [Transform methods for heavy-traffic analysis. Stochastic Systems 10(4):275–309], the statement of Claim 4 has a typo; it should say that the expression therein is bounded by a constant. The statement of Lemma 11, and Lemma 14 is incorrect.
Daniela Hurtado-Lange   +1 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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