Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley +1 more source
Diffusion approximation for an input-queued switch operating under a maximum weight matching policy
For N ≥ 2, we consider an N × N input-queued switch operating under a maximum weight matching policy. We establish a diffusion approximation for a (2N − 1)-dimensional workload process associated with this switch when all input ports and output ports are
Ruth J. Williams,, Weining Kang
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Effect of the Length of Traffic Flow Records on the Estimate of a Bridge Service Life
The service life of bridges is significantly affected by fatigue of used material induced by heavy vehicles. Therefore, precise determination of the vehicle weight is of crucial importance for the calculation of fatigue damage and the prediction of the ...
Krejsa Jan, Sykora Miroslav
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Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long +26 more
wiley +1 more source
Analysis of the Component-Based Reliability in Computer Networks
Performance in terms of reliability of computer networks motivates this paper. Limit theorems on the extreme queue length and extreme virtual waiting time in open queueing networks in heavy traffic are derived and applied to a reliability model for ...
Saulius Minkevi<img width=12 height=19 src="http:/fbpe/img/cubo/v12n1/img27.jpg">ius
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Network Throughput Gain of Multicast With User Caching in Heavy Traffic Downlink
In order to cope with the recent dramatic growth in mobile traffic, it is important to understand and exploit its unique features in wireless communications.
Jun-Pyo Hong, Seong Ho Chae, Kisong Lee
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Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
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HEAVY TRAFFIC ANALYSIS IN QUEUEING SYSTEMS
The traffic intensity is defined in the classical theory of queueing systems as the ratio of the expected service time and the expected interarrival time and is an important measure of the system performance.
USM ADMIN
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From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Bioconcentration of Heavy Metals in high Density traffic area of Port Harcourt Metopolis, Nigeria
The Bioconcentration factor (BCF) of selected heavy metals in grasses growing along High Density Traffic Area (HDTA) and Low Density Traffic Area (LDTA) of Port Harcourt metropolis was ascertained.
G Iwuoha, J Ogan, T Chikwe
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