Results 61 to 70 of about 584,932 (288)
Revista de la Facultad de Medicina, 2019 Introduction: Diseases such as asthma and lung cancer are associated with heavy traffic in urban areas. A deep understanding of the pollutants generated by road traffic is relevant to public health control.
Carlos Zafra-Mejía +2 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Peculiarities of metal work in the defect formation zone of a monoblock crossing
Вестник Научно-исследовательского института железнодорожного транспортаIntroduction. The paper analyses the causes of appearance and development of defects of the solid block with wing rails and welded rail ends (monoblock crossing) operating under heavy and intensive traffic conditions.
P. V. Tregubchak
doaj +1 more source
Heavy traffic analysis for EDF queues with reneging
, 2011 This paper presents a heavy-traffic analysis of the behavior of a single-server queue under an Earliest-Deadline-First (EDF) scheduling policy in which customers have deadlines and are served only until their deadlines elapse.
Kruk, Łukasz +3 more
core +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Conjectures on symmetric queues in heavy traffic
Queueing Systems, 2022 This note describes several open questions concerning scaling limits of queue-length processes of symmetric queues in heavy traffic, distinguishing between service-time distributions with finite and infinite variance.
openaire +3 more sources
Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Investigation of Weigh-in-Motion Measurement Accuracy on the Basis of Steering Axle Load Spectra
Sensors, 2019 Weigh-in-motion systems are installed in pavements or on bridges to identify and reduce the number of overloaded vehicles and minimise their adverse effect on road infrastructure.
Dawid Rys
doaj +1 more source
, 2019 A result of Ward and Glynn (2005) asserts that the sequence of scaled offered waiting time processes of the $GI/GI/1+GI$ queue converges weakly to a reflected Ornstein-Uhlenbeck process (ROU) in the positive real line, as the traffic intensity approaches
Lee, Chihoon +2 more
core +1 more source