Results 71 to 80 of about 47,318 (263)

Heavy traffic limits for queues with non-stationary path-dependent arrival processes. [PDF]

Queueing Syst, 2022
Fendick K, Whitt W.
europepmc   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

An ODE for an overloaded X model involving a stochastic averaging principle

Stochastic Systems, 2011
We study an ordinary differential equation (ODE) arising as the many-server heavy-traffic fluid limit of a sequence of overloaded Markovian queueing models with two customer classes and two service pools.
Ward Whitt, Ohad Perry
doaj  

The effect of residential proximity to brownfields, highways, and heavy traffic on serum metal levels in the Detroit Neighborhood Health Study. [PDF]

Environ Adv, 2022
Lodge EK, Guseh NS, Martin CL, Fry RC, White AJ, Ward-Caviness CK, Galea S, Aiello AE.   +7 more
europepmc   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

THE EXPERIENCE AND PROSPECTS OF THE DEVELOPMENT OF THE HEAVYWEIGHT MOVEMENT

International Journal of Advanced Studies
Background. The article is devoted to the review of the experience and analysis of the prospects for the development of the organization of the heavyweight movement.
Oksana D. Pokrovskaya, Oleg V. Shugaev
doaj   +1 more source

The Passenger Car Equivalent Factors for Heavy Vehicles on Turbo Roundabouts

Frontiers in Built Environment, 2019
The presence of heavy and slower vehicles within the traffic stream significantly reduces traffic capacity. This reduction increases with the higher participation of heavy vehicles in the stream, which, compared to passenger cars, move at a lower speed ...
Elżbieta Macioszek
doaj   +1 more source

Influence of Honking on the Road Traffic Noise Generated at Urban Rotaries for Heterogeneous Traffic

Environmental and Climate Technologies, 2020
This paper presents a study conducted at major rotaries for quantifying the traffic noise levels by considering the vehicle volume and their respective honking as governing parameters for heterogeneous traffic.
Aditya Kamineni, Chowdary Venkaiah
doaj   +1 more source

Proximity to Heavy Traffic Roads and Patient Characteristics of Late of Onset Asthma in an Urban Asthma Center. [PDF]

Front Med (Lausanne), 2021
Lin TY, Lin HC, Liu YS, Lo YL, Wang CH, Chang PJ, Lo CY, Lin SM.   +7 more
europepmc   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source