Results 181 to 190 of about 101,813 (256)

The role of the adenosinergic pathway in resistance to hypomethylating agents in patients with high‐risk myelodysplastic syndromes

open access: yes
British Journal of Haematology, EarlyView.
George Vrachiolias   +15 more
wiley   +1 more source

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Ldha Regulates Osteosarcoma Lung Metastasis through Hedgehog Signaling. [PDF]

open access: yesCancer Res Commun
Maki R   +6 more
europepmc   +1 more source

A 30‐year‐old woman with progressive lower extremity sensory loss and weakness

open access: yes
Brain Pathology, EarlyView.
Daniel W. Griepp   +4 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

Convergent use of aminopeptidase N receptor by hedgehog merbecoviruses. [PDF]

open access: yesNat Microbiol
Liu P   +24 more
europepmc   +1 more source

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