Results 161 to 170 of about 92,604 (309)
Food Chemistry International, EarlyView.Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique +3 more
wiley +1 more source
The role of GLI2 in human basal cell carcinoma tumourigenesis
, 2010 PhDAbnormal Sonic Hedgehog (SHH) signalling leads to increased transcriptional activation of its downstream effector, GLI2, which is implicated in the pathogenesis of a variety of human tumours, including human basal cell carcinoma (BCC).
Pantazi, Eleni
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Fast-tracking morphogen diffusion
, 2006 The readout of morphogen concentrations has been proposed to be an essential mechanism allowing embryos to specify cell identities (Wolpert Trends Genet 12 (1996) 359), but theoretical and experimental results have led to conflicting ideas as to how ...
Olivier Cinquin, Cinquin, O
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Mechanistic Studies of Vertebrate Hedgehog Signaling [PDF]
, 2013 Metazoans use Hedgehog signaling to direct many stages of embryonic development, and deregulation of this pathway is implicated in many types of cancer.
Tukachinsky, Hanna
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Intestinal Hedgehog signaling in tumors and inflammation [PDF]
, 2015 In this thesis we investigated the role of Hedgehog signaling in tumors and inflammation. By using an inducible Indian Hedgehog (Ihh) knockout mouse we show that Ihh signals via the mesenchyme to the proliferating cells in the crypt to attenuate ...
Büller, N.V.J.A.
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Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal +5 more
wiley +1 more source
Journal of Quaternary Science, EarlyView.ABSTRACT While competition with large carnivores is likely to have shaped Middle Paleolithic hominins' subsistence behavior, palimpsested human and carnivore accumulations render the signal challenging to isolate. This study presents a detailed zooarchaeological and taphonomic analysis of a non‐anthropogenic faunal assemblage from a MIS 5 (~130–80 ka ...
Meir Orbach +4 more
wiley +1 more source