Detection and molecular analysis of betacoronaviruses (family Coronaviridae) in hedgehogs (Erinaceus roumanicus) in Hungary. [PDF]
Reuter G +6 more
europepmc +1 more source
Locally Advanced Basal Cell Carcinoma With Orbital Invasion: Treatment With Neoadjuvant Hedgehog Pathway Inhibition and Palliative Enucleation. [PDF]
Murphy MA.
europepmc +1 more source
A 30‐year‐old woman with progressive lower extremity sensory loss and weakness
Brain Pathology, EarlyView.
Daniel W. Griepp +4 more
wiley +1 more source
Alongshan virus in the virome of Ixodes hexagonus ticks in the United Kingdom.
Jones BP +5 more
europepmc +1 more source
RETRACTION: Resveratrol Downregulates Interleukin-6-Stimulated Sonic Hedgehog Signaling in Human Acute Myeloid Leukemia. [PDF]
And Alternative Medicine EC.
europepmc +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source
Activated Hedgehog signaling in keratocytes leads to stromal stiffness and impairs corneal regeneration. [PDF]
Yu Q +7 more
europepmc +1 more source
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
A characterization of axolotl digit regeneration: conserved mechanisms, divergent patterning, and a critical role for hedgehog signaling. [PDF]
Griffiths JR +4 more
europepmc +1 more source

