Results 221 to 230 of about 201,870 (394)

Robustness of the hedgehog Skyrmion

open access: yesJournal of High Energy Physics
Abstract We investigate the radial profile function of the hedgehog Skyrmion with unit baryon number in generic EFTs (effective field theories) of pions. The analysis assumes chiral symmetry and ignores the pion mass term. The Skyrmion is always smooth, because it has no point source at the origin, and terms in the EFT with higher ...
openaire   +4 more sources

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

open access: yesNature Reviews Clinical Oncology, 2015
N. Takebe   +7 more
semanticscholar   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

The Mutational Spectrum of the Sonic Hedgehog Gene in Holoprosencephaly: SHH Mutations Cause a Significant Proportion of Autosomal Dominant Holoprosencephaly [PDF]

open access: bronze, 1999
Luisa Nanni   +16 more
openalex   +1 more source

Effect of Naringenin on Potassium Bromate–Induced Hepatotoxicity In Vivo: A Dose‐Dependent Study

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Potassium bromate (PB) is a well‐known additive in the food industry and a byproduct of water treatment. Its long‐term exposure to any form of life exerts mild to severe toxic insults in a dose‐dependent fashion and can even trigger carcinogenesis.
Iftekhar Hassan   +6 more
wiley   +1 more source

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