Expression of Sonic hedgehog gene in regenerating newt limb blastemas recapitulates that in developing limb buds [PDF]
Yutaka Imokawa, Katsutoshi Yoshizato
openalex +1 more source
Robustness of the hedgehog Skyrmion
Abstract We investigate the radial profile function of the hedgehog Skyrmion with unit baryon number in generic EFTs (effective field theories) of pions. The analysis assumes chiral symmetry and ignores the pion mass term. The Skyrmion is always smooth, because it has no point source at the origin, and terms in the EFT with higher ...
openaire +4 more sources
Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
N. Takebe+7 more
semanticscholar +1 more source
Induction of sonic hedgehog and patched by retinoic acid in the developing rat lung in vitro. • 292 [PDF]
Margaret Rush, Douglas Perkins
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Histological Study on the Innervation, especially on the Sensory Innervation of the Lung in Hedgehog
Hideo HONMA
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Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. [PDF]
Christina Alexandre+2 more
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Mechanisms of enhancer‐driven oncogene activation
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend+2 more
wiley +1 more source
The Mutational Spectrum of the Sonic Hedgehog Gene in Holoprosencephaly: SHH Mutations Cause a Significant Proportion of Autosomal Dominant Holoprosencephaly [PDF]
Luisa Nanni+16 more
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Effect of Naringenin on Potassium Bromate–Induced Hepatotoxicity In Vivo: A Dose‐Dependent Study
ABSTRACT Potassium bromate (PB) is a well‐known additive in the food industry and a byproduct of water treatment. Its long‐term exposure to any form of life exerts mild to severe toxic insults in a dose‐dependent fashion and can even trigger carcinogenesis.
Iftekhar Hassan+6 more
wiley +1 more source