Results 121 to 130 of about 1,401 (218)
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
Med Research, EarlyView.The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang +7 more
wiley +1 more source
An unusual choanoflagellate protein released by Hedgehog autocatalytic processing [PDF]
, 2005 Elizabeth A. Snell +5 more
openalex +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
Aberrant methylation of the human hedgehog interacting protein (HHIP) gene in pancreatic neoplasms [PDF]
, 2005 Seán T. Martin +7 more
openalex +1 more source
People and Nature, EarlyView.Abstract Overexploitation of wildlife is pervasive in many tropical regions, and in addition to being a significant conservation and sustainability concern, it has received global attention given discussions over the origins of zoonotic disease outbreaks.
Franklin T. Simo +8 more
wiley +1 more source
Wild meat consumption in changing rural landscapes of Indonesian Borneo
People and Nature, EarlyView.Abstract Wild meat can play a crucial role in the food system of rural communities residing near tropical forests. Yet, socio‐ecological changes across tropical landscapes are impacting the patterns and sustainability of meat consumption. To understand the prevalence, frequency and drivers of wild meat, domestic meat and fish consumption in this ...
Katie L. Spencer +12 more
wiley +1 more source
Introduction: Preface to the Hedgehog family of proteins review volume
, 2000 Philip W. Ingham, Marysia Placzek
openalex +2 more sources
The Cell Surface Membrane Proteins Cdo and Boc Are Components and Targets of the Hedgehog Signaling Pathway and Feedback Network in Mice [PDF]
, 2006 Toyoaki Tenzen +5 more
openalex +1 more source
Small Methods, EarlyView.Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai +9 more
wiley +1 more source
Nanotechnology and cell death: Revolutionizing disease treatment with nanoparticle strategies
VIEW, EarlyView.Traditional disease treatments often face issues such as poor drug targeting and significant side effects, with many complex diseases lacking effective therapies. Our research utilizes tiny nanomaterials to treat diseases by regulating natural cell death processes, improving the immune environment, etc., enabling drugs to act more precisely.
Yiwen Wan +6 more
wiley +1 more source