Results 171 to 180 of about 1,401 (218)
Osteochondrosis in horses: An overview of genetic and other factors
Equine Veterinary Journal, EarlyView.Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez +2 more
wiley +1 more source
Emerging roles for integrated stress response signaling in homeostasis
The FEBS Journal, EarlyView.Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan +5 more
wiley +1 more source
Mechanistic insights into dental stem cells‐derived exosomes in regenerative endodontics
International Endodontic Journal, EarlyView.Abstract Background Dental pulp is a richly vascularised and innervated tissue vital for tooth vitality, sensory function, and structural integrity. While conventional root canal therapy effectively treats necrotic permanent teeth, it irreversibly eliminates pulp vitality, potentially increasing the risk of secondary infections and long‐term structural
Paras Ahmad +4 more
wiley +1 more source
Journal of Animal Breeding and Genetics, EarlyView.ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei +4 more
wiley +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Early Skin Biopsy in Conradi‐Hünermann‐Happle Syndrome (X‐Linked Dominant Chondrodysplasia Punctata)
Journal of Cutaneous Pathology, EarlyView.
Cathal O'Connor +4 more
wiley +1 more source
Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View
Orthodontics &Craniofacial Research, EarlyView.ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai +4 more
wiley +1 more source