Results 211 to 220 of about 100,157 (319)

GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer

open access: yesCell Proliferation, EarlyView.
GANT61 induced autophagy via the AKT pathway and promoted the accumulation of lipid droplets in both cell lines. The molecular mechanism behind this lipid accumulation appears to involve the mediation of SREBP1. Furthermore, the combination of GANT61 with CQ/Fatostatin significantly inhibited the proliferation and clonogenicity of SKOV3 and SKOV3PTX ...
Yibin Pan   +13 more
wiley   +1 more source

Transforming growth factor‐β‐mediated regulation of atoh1‐expressing neural progenitors is involved in the generation of cerebellar granule cells in larval and adult zebrafish

open access: yesDevelopment, Growth &Differentiation, Volume 67, Issue 3, Page 149-164, April 2025.
Proliferating neural progenitor cells that generate granule cells are located in the molecular layer (ML) of the cerebellum. Among these, some atoh1c‐expressing cells begin to differentiate and migrate to the granular layer (GL), where they localize as mature granule cells.
Jui Chun Wang   +2 more
wiley   +1 more source

Sonic Hedgehog Shedding Results in Functional Activation of the Solubilized Protein [PDF]

open access: bronze, 2011
Stefanie Ohlig   +11 more
openalex   +1 more source

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik   +5 more
wiley   +1 more source

Importance of hedgehog interacting protein and other lung function genes in asthma [PDF]

open access: bronze, 2011
Xingnan Li   +19 more
openalex   +1 more source

A review of the equine suspensory ligament: Injury prone yet understudied

open access: yesEquine Veterinary Journal, EarlyView.
Abstract The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion.
Deborah J. Guest   +2 more
wiley   +1 more source

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