Results 201 to 210 of about 55,658 (256)

Advancing gambogic acid for translational oncology: Redox–proteostasis collapse, multidrug resistance reversal, nanodelivery and biomarker‐guided development

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Gambogic acid exerts anticancer effects through reactive oxygen species‐mediated apoptosis, suppression of nuclear factor kappa B and phosphatidylinositol‐3‐kinase–protein kinase B signalling, multidrug resistance modulation and tumour microenvironment effects.
Uttam Singh Baghel, Kajal Gurow, Geetanjali Mehara, Priyanka Kriplani, Neelam M. Patel, Abhay Sharma, Deeksha Singh, Atamjit Singh, Suchi Dave, Bhawani Singh, Lashyn N. Kiyekbayeva, William N. Setzer, Javad Sharifi‐Rad, Cheryl Grace Pratiwi Rumahorbo, Daniela Calina   +14 more
wiley   +1 more source

The Hippo signaling pathway in pediatric brain tumors: molecular mechanisms and therapeutic opportunities. [PDF]

Cancer Metastasis Rev
Papanikolaou MA, Gargalionis AN, Adamopoulos C, Piperi C.   +3 more
europepmc   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, Volume 255, Issue 8, Page 808-823, August 2026.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Effects of fatty acids and cholesterol on functions and behavior of bone marrow mesenchymal stem cells. [PDF]

iScience
Gonzalez-Garcia B, Plaza M, Fresco M, Aparicio C, Abia R, Muriana FJG, Jaramillo-Carmona SM.   +6 more
europepmc   +1 more source

Sphingosine‐1‐Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex

Glia, Volume 74, Issue 8, August 2026.
Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales, Connor Tuck, Surya Chandra Rao Thumu, Soha Munir, Jaden Harris, Hunain (Zeik) Tariq, Paul Marcelli, Oscar Dominguez, Kaviya Suriyakumar Anbazagan, Sandeep K. Singh   +9 more
wiley   +1 more source

7-Ketocholesterol Links Sterol Homeostasis to Hedgehog Signaling and Stress-Survival Responses in MSCs from Patients with Acute Myeloid Leukemia. [PDF]

Int J Mol Sci
Reichert CO, Levy D, Freitas FA, Silva JS, Barros PL, Paz JL, Nunes JPS, Cunha-Neto E, Kalil J, Giglio PN, Demange MK, Culler HF, Lage LAPC, Rodrigues A, Pereira J, Bydlowski SP.   +15 more
europepmc   +1 more source

Ultradeformable liposomal delivery of vismodegib modulates its biological activity in melanoma cells. [PDF]

Front Med Technol
Calienni MN, Sandoval-Acuña C, Potomová P, Ybarra DE, Truksa J, Montanari J.   +5 more
europepmc   +1 more source

Activated Hedgehog signaling in keratocytes leads to stromal stiffness and impairs corneal regeneration. [PDF]

NPJ Regen Med
Yu Q, Li P, Du Z, Che M, Zhao H, Li B, Zhao P, Li J.   +7 more
europepmc   +1 more source

Detection and molecular analysis of betacoronaviruses (family Coronaviridae) in hedgehogs (Erinaceus roumanicus) in Hungary. [PDF]

Arch Virol
Reuter G, Cora CE, Takáts K, Boros Á, Mátics R, Balázs B, Pankovics P.   +6 more
europepmc   +1 more source

Gene Expression During Scale Development in Pachyrhynchus Weevils. [PDF]

J Exp Zool B Mol Dev Evol
Chen YC, Chen YR, Amarga AKS, Tseng HY.
europepmc   +1 more source