Results 221 to 230 of about 100,157 (319)

Sonic Hedgehog-induced Proliferation Requires Specific Gα Inhibitory Proteins [PDF]

, 2011
Mercedes Barzi, Dorota Kostrz, Anghara Menéndez, Sebastián Pons   +3 more
openalex   +1 more source

Inherited non‐syndromic polydactyly in a Berber and Arabian‐Berber horse family

Equine Veterinary Journal, EarlyView.
Abstract Background Supernumerary digits, or polydactyly, have been described in various species including humans, wild and domestic animals. In horses, it represents the most common congenital limb malformation, which has only been described in isolated cases or nuclear families. Molecular aetiology has not been reported.
Ella Baville, Bianca Carstanjen, Aurélie Thomas‐Cancian, Anne Calgaro, Nathale Bonnet, Laurent Tiret, Vincent Gache, Marie Abitbol   +7 more
wiley   +1 more source

Hedgehog and PI3K/Akt/mTOR Signaling Pathways Involvement in Leukemic Malignancies: Crosstalk and Role in Cell Death. [PDF]

Cells
Sicurella M, De Chiara M, Neri LM.
europepmc   +1 more source

Highlighted article: “Indian Hedgehog Positively Regulates Calvarial Ossification and Modulates Bone Morphogenetic Protein Signaling” by K. Lenton, A. W. James, A. Manu, S. A. Brugmann, D. Birker, E. R. Nelson, P. Leucht, J. A. Helms and M. T. Longaker [PDF]

, 2011

openalex   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

Equine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez, Pablo J. Marín‐García, M. Lola Llobat   +2 more
wiley   +1 more source

Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer. [PDF]

Cell Death Discov
Cong G, Zhu X, Chen XR, Chen H, Chong W.
europepmc   +1 more source

Therapeutic targeting of TGF‐β in lung cancer

The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.
Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi, Amir Barzegar Behrooz, Marco Cordani, Niloufar Rahiman, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Stephen Pistorius, Seyedeh Hoda Alavizadeh, Nima Taefehshokr, Saeid Ghavami   +9 more
wiley   +1 more source

Deciphering the potential of plant metabolites as insecticides against melon fly (Zeugodacus cucurbitae): Exposing control alternatives to assure food security. [PDF]

Heliyon
Chowdhury ZJ, Banik A, Robin TB, Chowdhury MR.   +3 more
europepmc   +1 more source

14-3-3 Proteins Regulate a Cell-Intrinsic Switch from Sonic Hedgehog-Mediated Commissural Axon Attraction to Repulsion after Midline Crossing [PDF]

, 2012
Patricia T. Yam, Christopher B. Kent, Steves Morin, W. Todd Farmer, Ricardo Alchini, Léa Lepelletier, David Colman, Marc Tessier‐Lavigne, Alyson E. Fournier, Frédéric Charron   +9 more
openalex   +1 more source

Atypical MAPKs in cancer

The FEBS Journal, Volume 292, Issue 9, Page 2173-2188, May 2025.
Mitogen‐activated protein kinases (MAPKs) regulate various cellular processes, including proliferation, differentiation, and motility. Alterations in these signalling pathways can lead to various diseases, including cancer. The atypical MAPKs ERK3 (MAPK6), ERK4 (MAPK4), ERK7/8 (MAPK15) and NLK have long been neglected in kinomic studies.
Katrin Dahm, Parthiban Vijayarangakannan, Hans‐Peter Wollscheid, Hansjörg Schild, Krishnaraj Rajalingam   +4 more
wiley   +1 more source