Results 191 to 200 of about 58,953 (264)

Etymology and entomology: The semiotics and ethics of multispecies gene nomenclatures

Journal of Linguistic Anthropology, Volume 36, Issue 2, August 2026.
Abstract This article examines controversies surrounding gene names that are perceived as humorous in the context of fruit flies but are considered rude in the clinical context of human medicine. Drawing on ethnographic fieldwork in insect laboratories, interviews with entomologists and geneticists, and an analysis of scientific and clinical ...
Colin M. E. Halverson
wiley   +1 more source

TRV130 inhibits colon cancer progression via suppressing the Hedgehog signaling pathway: in vitro and in vivo evidence. [PDF]

Hereditas
Zhuang Y, Jiang C, Guo Y, Sun J.
europepmc   +1 more source

Oestrogen receptor phosphorylation profiles and in silico PAM50 subtyping reflect sexual dimorphism in breast cancer

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Breast cancer (BC) is most prevalent in females but also accounts for <1% of male cancer cases and 0.2% of male cancer‐related deaths. Distribution of histological subtypes, receptor status, and age of diagnosis varies based on sex, and a growing body of evidence supports sex‐specific molecular differences in BC.
Subarnarekha Chatterji, Aimee Diack, Marcin Szostok, Michael D Morgan, Valentina Silvestri, Laura Ottini, Cathy B Moelans, Paul J van Diest, Cigdem Selli, Andrew H Sims, Rasha Abu‐Eid, Valerie Speirs   +11 more
wiley   +1 more source

Hedgehog signaling pathway is an influential factor on vascular biology: a review. [PDF]

J Physiol Biochem
Ai M, Xiao L, Yu Y, Wu L, Yu OY, Cao Y, Liu J, Song K.   +7 more
europepmc   +1 more source

Pan‐TRK expression and NTRK gene aberrations in meningiomas: association with tumor grade and proliferative activity

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Tropomyosin receptor kinase (TRK) fusions are actionable oncogenic drivers, and pan‐TRK immunohistochemistry (IHC) serves as a reliable screening tool for NTRK gene aberrations. However, the expression profile and clinical significance of pan‐TRK in meningiomas remain unclear.
Yinan Zhu, Mingfang Sun, Wanchen Lu, Ziyue Wang, Haiyan Xi, Yan Song, Hongtao Xu, Xuyong Lin   +7 more
wiley   +1 more source

IFT139 regulates Hedgehog signaling and cilia structure through ciliary protein localization. [PDF]

Biol Open
Nishat K, Klug Z, Faimma Mia J, Stump SM, Cherry Liu Y.   +4 more
europepmc   +1 more source

Combined Long‐Read Genome and Transcriptome Sequencing Establishes Novel Variants in MEGF8 as the Cause for Carpenter Syndrome Type 2

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1719-1724, July 2026.
ABSTRACT Carpenter syndrome type 2 (CRPT2) is a rare autosomal recessive disease mainly characterized by craniosynostosis and polysyndactyly. CRPT2 is the rarer subtype of Carpenter syndrome (CRPTS) and is caused by biallelic variants in the multiple epidermal growth factor‐like domains 8 gene (MEGF8).
Kiana Rashidi, Bhavi P. Modi, Phillip A. Richmond, Massimo Mangino, Loryn Byres, Cassie McDonald, Joshua Dalmann, Simran Samra, Kate L. Del Bel, Anna Lehman, Jessica L. Zambonin, Stuart E. Turvey   +11 more
wiley   +1 more source

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression. [PDF]

Front Cell Dev Biol
Baidya S, Barua U, Shanto MR, Sonia TS, Amin MA, Sultana S, Jerin N, Jahan K, Jahan I, Ahmed S, Moinul Islam M, Parial R, Hossain MM, Noman ASM.   +13 more
europepmc   +1 more source

Primary cilia–extracellular vesicle crosstalk in Alzheimer's disease: Emerging mechanisms and biomarker potential

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Alzheimer's disease (AD) is a neurodegenerative condition marked by cognitive decline and synaptic issues. Recent studies show primary cilia (PCs), sensory organelles present on the surface of most mammalian cells, act as a critical regulators of brain homeostasis and signaling.
Vishal Singh Guleria, Charisse N. Winston   +1 more
wiley   +1 more source

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD. [PDF]

Front Cell Dev Biol
Petit LMG, Belgacemi R, Mulette P, Brisebarre A, Saber Cherif L, Devilliers MA, Hatoum S, Ancel J, Delepine G, Durlach A, Polette M, Deslée G, Perotin JM, Dormoy V.   +13 more
europepmc   +1 more source