Results 191 to 200 of about 107,152 (254)

“Is This Edible Anyway?” The Impact of Culture on the Evolution (and Devolution) of Mushroom Knowledge

Topics in Cognitive Science, EarlyView.
Abstract Mushrooms are a ubiquitous and essential component in our biological environment and have been of interest to humans around the globe for millennia. Knowledge about mushrooms represents a prime example of cumulative culture, one of the key processes in human evolution.
Andrea Bender, Åge Oterhals
wiley   +1 more source

Hedgehog signaling pathway is an influential factor on vascular biology: a review. [PDF]

J Physiol Biochem
Ai M, Xiao L, Yu Y, Wu L, Yu OY, Cao Y, Liu J, Song K.   +7 more
europepmc   +1 more source

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson, Kala A. Early, Maritza A. Morales, Klaudia A. Poplawski, Sunetra Das, Dawn L. Duval   +5 more
wiley   +1 more source

METTL3-mediated activation of Sonic Hedgehog signaling promotes breast cancer progression. [PDF]

Front Cell Dev Biol
Baidya S, Barua U, Shanto MR, Sonia TS, Amin MA, Sultana S, Jerin N, Jahan K, Jahan I, Ahmed S, Moinul Islam M, Parial R, Hossain MM, Noman ASM.   +13 more
europepmc   +1 more source

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, EarlyView.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

NFKBIE as a prognostic biomarker and therapeutic target for GBM: role in Hedgehog signaling activation. [PDF]

BMC Cancer
Mo F, Li Y, Dong C, Yang L, Ma X, Pan B, Fan Z.   +6 more
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD. [PDF]

Front Cell Dev Biol
Petit LMG, Belgacemi R, Mulette P, Brisebarre A, Saber Cherif L, Devilliers MA, Hatoum S, Ancel J, Delepine G, Durlach A, Polette M, Deslée G, Perotin JM, Dormoy V.   +13 more
europepmc   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

AXL-Driven Stemness and Hedgehog Signaling in HER2-Positive Breast Cancer with Acquired Trastuzumab Resistance: Synergistic Potential of AXL and HER2 Co-Targeting. [PDF]

Life (Basel)
Boz AB, Er I, Picher EA, Smarakan S.
europepmc   +1 more source