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Hedgehog: an unusual signal transducer
BioEssays, 2004AbstractHedgehog proteins are of pivotal importance for development and maintenance of tissue patterns in adult organisms. Despite the role of Hedgehogs in differentiation and tumorigenesis, signal transduction of Hedgehog remains a relatively uncharted area of signalling biochemistry.
Maarten F, Bijlsma +2 more
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The mechanism of hedgehog signal transduction
Biochemical Society Transactions, 2005Hedgehog (Hh) proteins are one of a small number of families of secreted signalling proteins that are responsible for cell interactions during development in many animals. As such, Hh signals produce many different responses at different times and in different cells.
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Phosphorylation Regulation of Hedgehog Signaling
2012The study of posttranslational regulation of proteins has occupied biochemists for well over a half century. Understanding balanced phosphorylation and dephosphorylation of the proteins may be the key to meeting some of the most pressing scientific challenges. A detailed examination of the phosphorylation of many components in the Hedgehog (Hh) pathway
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Apatite-Binding Nanoparticulate Agonist of Hedgehog Signaling for Bone Repair
Advanced Functional Materials, 2020Chung-Sung Lee, Xiao Zhang, Tara Aghaloo
exaly
Hedgehog signaling underlying tendon and enthesis development and pathology
Matrix Biology, 2022Andrew J Luzzi +2 more
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Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis
Cell, 2017Daniel Kopinke +2 more
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Similarities between the Hedgehog and Wnt signaling pathways
Trends in Cell Biology, 2002Daniel Kalderon
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