Results 241 to 250 of about 956,727 (289)

7-Ketocholesterol Links Sterol Homeostasis to Hedgehog Signaling and Stress-Survival Responses in MSCs from Patients with Acute Myeloid Leukemia. [PDF]

Int J Mol Sci
Reichert CO, Levy D, Freitas FA, Silva JS, Barros PL, Paz JL, Nunes JPS, Cunha-Neto E, Kalil J, Giglio PN, Demange MK, Culler HF, Lage LAPC, Rodrigues A, Pereira J, Bydlowski SP.   +15 more
europepmc   +1 more source

Loss of SPECC1L in cranial neural crest cells results in increased hedgehog signaling and frontonasal dysplasia. [PDF]

Front Physiol
Tran AJ, Hufft-Martinez BM, Thalman DN, Maili L, McKinney SA, Goering JP, Trainor PA, Saadi I.   +7 more
europepmc   +1 more source

Epigenetic regulation of TIPE3 in nasopharyngeal carcinoma and its impact on the hedgehog signaling pathway. [PDF]

Cell Mol Life Sci
Cheng Z, Fang Z, Yue K, Guo Y, Huang L, Zhang Y.   +5 more
europepmc   +1 more source

Gedunin Impacts Pancreatic Cancer Stem Cells Through the Sonic Hedgehog Signaling Pathway. [PDF]

Pharmaceuticals (Basel)
Perez K, Rodriguez S, Barragan J, Narayanan P, Ruiseco A, Rajkumar P, Ramirez N, Vasquez V, Lakshmanaswamy R, Subramani R.   +9 more
europepmc   +1 more source

Sonic Hedgehog signaling in oligodendrogenesis, myelination, demyelinating diseases, and remyelination. [PDF]

Neural Regen Res
Marchena-Fernández M, Sánchez-Camacho C, Muñoz-Sáez E, Macías-Castellano A, de Castro Soubriet F.   +4 more
europepmc   +1 more source

Multifaceted role of primary cilia and ciliary proteins: A potential nexus for hedgehog signaling and prostate cancer. [PDF]

Biochim Biophys Acta Mol Basis Dis
Kaushal JB, Seshacharyulu P, Batra SK, Muniyan S.   +3 more
europepmc   +1 more source

Hedgehog Signaling in Hematopoiesis [PDF]

Critical Reviews in Eukaryotic Gene Expression, 2010
The Hedgehog signaling pathway is highly conserved and plays an essential role in the embryonic development of a wide variety of organs. In adult tissues, such as the central nervous system, it may also be required for homeostasis and repair following injury. The role of Hedgehog signaling in regulating hematopoiesis is not entirely clear. Evidence has
William Matsui, Yiting Lim
exaly   +3 more sources

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Hedgehog Signaling in the Prostate

Journal of Urology, 2007
Recent discoveries highlight the importance of the hedgehog signaling pathway in prostate growth regulation. We reviewed the role of hedgehog signaling in prostate development, adult prostate homeostasis and prostate cancer.A comprehensive review of all relevant literature was done.Epithelial expression of hedgehog ligand during prostate development ...
Aubie, Shaw, Wade, Bushman
openaire   +2 more sources

On the range of Hedgehog signaling

Current Opinion in Genetics & Development, 2000
Hedgehog (Hh) is a secreted signaling protein that regulates the development of many organ systems. It can travel from its site of synthesis, a process that involves covalent attachment of cholesterol to its carboxyl terminus, proteins with putative sterol sensing domains in both sending and receiving cells, and glycosaminoglycans.
P T, Chuang, T B, Kornberg
openaire   +2 more sources

Hedgehog Signaling Pathway

Science's STKE, 2007
The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.
Leni, Jacob, Lawrence, Lum
openaire   +2 more sources