Results 221 to 230 of about 107,152 (254)

miR-433 targets BMP and Indian Hedgehog signaling to coordinate murine postnatal growth plate dynamics. [PDF]

J Bone Miner Res
Thakore P, Smith SS, Karki S, Guzzo R, Delany AM.   +4 more
europepmc   +1 more source

Transition From Land to Sea: Comparative Genomics Illuminates the Adaptive Evolution of the Intertidal Spider

Molecular Ecology Resources, Volume 26, Issue 4, May 2026.
ABSTRACT Spiders are renowned for their ecological versatility and silk‐based innovations in materials science, yet marine environments remain virtually uncolonized by this predominantly terrestrial lineage. A striking exception is the obligate intertidal spider genus Desis, whose members have evolved extraordinary physiological and behavioural ...
Fan Li, Yunyun Lv, Chao Bian, Quentin Moana Perrin, Yubo Zhang, Yixiao Wang, Lei Cao, Long Yu, Shengtao Guo, Wei Zhang, Qiong Shi, Daiqin Li   +11 more
wiley   +1 more source

Identification of RPGRIP1L as an instability-maintaining gene to drive tumor growth and PD-L1 expression via Hedgehog signaling in breast cancer. [PDF]

BMC Cancer
Lv M, Liu Y, Cao W, Wang Y, Wang Q, Gao X, Peng B, Wang H, Mao Y.   +8 more
europepmc   +1 more source

Maladaptive Inflammatory Signaling in Old Mice Impairs Colonic Regeneration by Promoting a Sustained Fetal‐Like Epithelial State

Aging Cell, Volume 25, Issue 5, May 2026.
This study explores the impact of aging on regeneration of the mouse colonic epithelium. The authors find that old mice exhibit excessive and prolonged inflammation after infection with Citrobacter, resulting in the maintenance of a fetal regenerative state in epithelial cells, insufficient tissue repair, and death of the animal.
Antonion Korcari, Helen Tauc, Jeff Duggan, Jina Yun, Fabien Wehbe, Spyros Darmanis, Zora Modrusan, Rajita Pappu, David Garfield, Heinrich Jasper, David Castillo‐Azofeifa   +10 more
wiley   +1 more source

Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer. [PDF]

Int J Mol Sci
Manoukian P, Damhofer H, Zhao L, van Laarhoven HWM, Bijlsma MF.   +4 more
europepmc   +1 more source

Interleukin‐10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways

Cell Proliferation, Volume 59, Issue 5, May 2026.
IL10_ApoEVs, generated during IL‐10‐induced fibroblast apoptosis, reprogram fibroblast metabolism and inhibit fibrosis to promote scarless skin healing. By enhancing mitochondrial OXPHOS, suppressing glycolysis, and downregulating Hedgehog signaling, IL10_ApoEVs shift collagen deposition toward regenerative type III collagen, offering a novel strategy ...
Yang Zou, Jinglun Zhang, Wenxuan Mao, Shuting Jiang, Cheng Xu, Jiayi Meng, Heng Dong, Yongbin Mou   +7 more
wiley   +1 more source

Dual-Lineage Chondrocyte-Like Cells in the Nucleus Pulposus of Aging Intervertebral Discs Are Accelerated by Hedgehog Signaling Inactivation. [PDF]

Aging Cell
Zhang L, Xiu C, You H, Chen J.
europepmc   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G., Kamini Shivhare, Piyush Kumar Gupta, Amirhossein Sahebkar, Prashant Kesharwani, Rahul Shukla   +5 more
wiley   +1 more source

DNA-mediated ZNF649 downregulation modulates the Hedgehog signaling pathway to reduce the sensitivity of gastric cardia cancer to 5-FU. [PDF]

J Clin Biochem Nutr
Xia G, Li B, Liang X, Wan Y, Liu Z.
europepmc   +1 more source

Computed Tomography Findings of Migrating Grass Awn Leading to Esophageal Perforation and Carotid Artery Erosion in a Dog

Veterinary Radiology &Ultrasound, Volume 67, Issue 3, May 2026.
ABSTRACT A 4‐year‐old male intact Kerry Blue Terrier presented with lethargy, pyrexia, intermittent cough, and a large, firm right ventral cervical mass. Contrast‐enhanced head and neck CT revealed a focally expansile, ill‐defined, mixed‐attenuation lesion with gas bubbles, suggestive of extensive cellulitis and abscessation, in close communication ...
Flavia Thaysa Vieira Freitag, Jennifer Marie Loewen, Gwo‐Yuan Yang, Yasmine Messiaen, Jasmine Yu Gu   +4 more
wiley   +1 more source