Mechanistic insights into dental stem cells‐derived exosomes in regenerative endodontics
Abstract Background Dental pulp is a richly vascularised and innervated tissue vital for tooth vitality, sensory function, and structural integrity. While conventional root canal therapy effectively treats necrotic permanent teeth, it irreversibly eliminates pulp vitality, potentially increasing the risk of secondary infections and long‐term structural
Paras Ahmad+4 more
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Primary Cilia Formation Mediated by Hsa_Circ_0005185/OTUB1/RAB8A Complex Inhibits Prostate Cancer Progression by Suppressing Hedgehog Signaling Pathway. [PDF]
Fan A+7 more
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NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of H<sub>2</sub>S into the synovium. [PDF]
Zhu XX+20 more
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Characterization of Esrrb function in metastatic prostate cancer cells and transcriptional regulation of hedgehog-signaling pathway target genes [PDF]
Lu Yuan
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ABSTRACT Swedish Warmblood horses (SWB) are bred for show jumping and/or dressage with young horse test scores as indicator traits. This study aimed to investigate possible candidate genes and regions of importance for evaluated and linearly scored young horse test traits.
Anahit Nazari‐Ghadikolaei+4 more
wiley +1 more source
Interactions between hedgehog signaling pathway and the complex tumor microenvironment in breast cancer: current knowledge and therapeutic promises. [PDF]
Liu R+8 more
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The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag+6 more
wiley +1 more source
The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway. [PDF]
Zhao X+5 more
europepmc +1 more source
MiR-875-5p suppresses Gli1 to alter the hedgehog signaling pathway, which in turn has hepatocellular cancer-related tumor suppressing properties. [PDF]
Zhang Q, Yu M, Yang L, Sun D.
europepmc +1 more source