Results 291 to 300 of about 834,809 (383)

Combined effects of EGFR and Hedgehog signaling pathway inhibition on the proliferation and apoptosis of pancreatic cancer cells

, 2012
Chang-fu Qin, Kun Hao, Xiaodong Tian, Xuehai Xie, Yinmo Yang   +4 more
openalex   +2 more sources

Interactions between hedgehog signaling pathway and the complex tumor microenvironment in breast cancer: current knowledge and therapeutic promises. [PDF]

Cell Commun Signal
Liu R, Yu Y, Wang Q, Zhao Q, Yao Y, Sun M, Zhuang J, Sun C, Qi Y.   +8 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways [PDF]

, 2015
Li Song, Meirong Zhao, Jianxin Liu, Zhuoyu Li, Hong Xiao, Weiping Liu   +5 more
openalex   +1 more source

The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway. [PDF]

Open Med (Wars)
Zhao X, Shao X, Huang X, Dang C, Wang R, Li H.   +5 more
europepmc   +1 more source

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway. [PDF]

J Assist Reprod Genet
Liu M, Wang X, Zhu J.
europepmc   +1 more source

Utilising Next‐Generation Sequencing to Explore the Molecular Etiology of Short Root Anomaly

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Short Root Anomaly (SRA) is a genetic dental disorder affecting tooth root development. The affected teeth have abnormally short roots and significantly reduced root to crown ratios. The aim of this study was to determine the mode of inheritance and the molecular aetiology of SRA in identified Hispanic families.
Emily A. Joy, David K. Crossman, Mary MacDougall, Quamarul Hassan, Ejvis Lamani   +4 more
wiley   +1 more source

Activation of the sonic hedgehog signaling pathway occurs in the CD133 positive cells of mouse liver cancer Hepa 1–6 cells

, 2013
Kuo‐Shyang Jeng, I‐Shyan Sheen, Ming-Che Yu, Hsin-I Hsiau, Fang‐Yu Chang, Hsin-Hua Tsai, Kuo‐Shyang Jeng   +6 more
openalex   +2 more sources

MiR-875-5p suppresses Gli1 to alter the hedgehog signaling pathway, which in turn has hepatocellular cancer-related tumor suppressing properties. [PDF]

Heliyon
Zhang Q, Yu M, Yang L, Sun D.
europepmc   +1 more source