Results 291 to 300 of about 247,901 (376)

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

Distraction force promotes the osteogenic differentiation of Gli1⁺ cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway. [PDF]

Stem Cell Res Ther
Jin M, An Y, Wang Z, Wang G, Lin Z, Ding P, Lu E, Zhao Z, Bi H.   +8 more
europepmc   +1 more source

Characterization of Esrrb function in metastatic prostate cancer cells and transcriptional regulation of hedgehog-signaling pathway target genes [PDF]

, 2014
Lu Yuan
openalex   +1 more source

Immunomodulation of salivary gland function due to cancer therapy

Oral Diseases, EarlyView.
Abstract Functional salivary glands (SG) are essential for maintaining oral health, and salivary dysfunction is a persistent major clinical challenge. Several cancer therapies also have off‐target effects leading to SG dysfunction. Recent advances highlight the role of SG immune populations in homeostasis, dysfunction and gland regeneration.
Ana C. Costa‐da‐Silva, Carlos U. Villapudua, Matthew P. Hoffman, Marit H. Aure   +3 more
wiley   +1 more source

MiR-875-5p suppresses Gli1 to alter the hedgehog signaling pathway, which in turn has hepatocellular cancer-related tumor suppressing properties. [PDF]

Heliyon
Zhang Q, Yu M, Yang L, Sun D.
europepmc   +1 more source

Combined effects of EGFR and Hedgehog signaling pathway inhibition on the proliferation and apoptosis of pancreatic cancer cells

, 2012
Chang-fu Qin, Kun Hao, Xiaodong Tian, Xuehai Xie, Yinmo Yang   +4 more
openalex   +2 more sources

Grape constituents for protection against photodamage to skin

Photochemistry and Photobiology, EarlyView.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon, Rubina Shafi, Allen Oak, Mohammad Athar, Andrzej Slominski, Craig A. Elmets   +5 more
wiley   +1 more source

Benzaldehyde stimulates autophagy via the sonic hedgehog signaling pathway in mouse brain astrocytes after treatment with Angiostrongylus cantonensis excretory-secretory products. [PDF]

Int J Parasitol Drugs Drug Resist
Chen KY, Cheng CJ, Chang YT, Lin YH, Huang YH, Lin SY, Wang LC, Jhan KY, Chiu CH.   +8 more
europepmc   +1 more source

p,p′-Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways [PDF]

, 2015
Li Song, Meirong Zhao, Jianxin Liu, Zhuoyu Li, Hong Xiao, Weiping Liu   +5 more
openalex   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source