Results 21 to 30 of about 132,829 (164)

The cell type dependent sorting of CD9- and CD81 to extracellular vesicles can be exploited to convey tumor sensitive cargo to target cells

open access: yesDrug Delivery, 2023
Extracellular vesicles (EVs) are lipid membrane-bound particles involved in cell-to-cell communication through a delivery of regulatory molecules essential for physiological processes.
Stefania Zuppone   +2 more
doaj   +1 more source

Inhibitory Effect of CCK-8 on Methamphetamine-Induced Apoptosis

open access: yesFayixue Zazhi, 2021
ObjectiveTo investigate the inhibitory effect of cholecystokinin octapeptide (CCK-8) binding to cholecystokinin 2 receptor (CCK2R) on methamphetamine (METH)-induced neuronal apoptosis, and to explore the signal transduction mechanism of β-arrestin 2 in ...
ZHANG Wu-hua   +8 more
doaj   +1 more source

N-Acetylcysteine Inhibits Patulin-Induced Apoptosis by Affecting ROS-Mediated Oxidative Damage Pathway

open access: yesToxins, 2021
Patulin (PAT) belongs to the family of food-borne mycotoxins. Our previous studies revealed that PAT caused cytotoxicity in human embryonic kidney cells (HEK293).
Jiayu Liu   +8 more
doaj   +1 more source

Effects of Fish Oil Combined with Cisplatin on HEK293 Cells and A549 Cells

open access: yesShipin gongye ke-ji, 2022
Objective: To explore the effect of fish oil on the activity of cis-dichlorodiamineplatinum (Ⅱ) (CDDP) against A549 human lung adenocarcinoma cells and its protective effect on HEK293 cells damaged by CDDP. Methods: A549 and HEK293 cells were cultured in
Yuemei DU   +3 more
doaj   +1 more source

The toxicogenic effect of Terminalia phanerophlebia Engl. & Diels leaf extract on oxidative stress parameters in an in vitro Hek293 model [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: Medicinal plants are a highly sought-after alternative to current pharmaceutical drugs because they can be locally cultivated, inexpensive and possess minimal adverse effects.
Marcilyn R. Nyahada   +5 more
doaj  

Myricetin inhibits Kv1.5 channels in HEK293 cells

open access: yesMolecular Medicine Reports, 2015
Myricetin (Myr) is a flavonoid that exerts anti-arrhythmic effects. However, its potential effects on ion channels have remained elusive. The aim of the present study was to investigate the effects of Myr on Kv1.5 channels in HEK293 cells. The current of Kv1.5 channels (Ikur) in HEK293 cells was recorded using the whole-cell patch-clamp technique and ...
Xianhong, Ou   +6 more
openaire   +3 more sources

Endogenous calcium channels in human embryonic kidney (HEK293) cells [PDF]

open access: yesBritish Journal of Pharmacology, 1996
We have identified endogenous calcium channel currents in HEK293 cells. Whole cell endogenous currents (ISr‐HEK) were studied in single HEK293 cells with 10 mM strontium as the charge carrier by the patch clamp technique. The kinetic properties and pharmacological features of ISr‐HEK were characterized and compared with the properties of a ...
S, Berjukow   +5 more
openaire   +2 more sources

Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10

open access: yesJournal of Pharmacological Sciences, 2022
OAT10 (SLC22A13) is a transporter highly expressed in renal tubules and transporting organic anions including nicotinate, β-hydroxybutyrate, p-aminohippurate, and orotate. In transport assays using Xenopus oocytes and HEK293 cells, we found that apparent
Naoko Ohtsu   +9 more
doaj   +1 more source

Clusterin purification from HEK293E cells v1 [PDF]

open access: yes, 2021
This protocol details the preocedure of clusterin purification from HEK293E cells.
openaire   +1 more source

Inducible HEK293 AAV packaging cell lines expressing Rep proteins

open access: yesMolecular Therapy - Methods & Clinical Development, 2023
Packaging or producer cell lines for scalable recombinant adeno-associated virus (rAAV) production have been notoriously difficult to create due in part to the cytostatic nature of the Rep proteins required for AAV production. The most difficult challenge being creating AAV packaging cell lines using HEK293 parental cells, currently the best mammalian ...
Jalšić, Lovro   +7 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy