Results 31 to 40 of about 4,870,076 (306)

Biological characterization of HEK293-C34 cells and SARS-CoV-2.

, 2023
(A) Growth kinetics of HEK293-C34 cells. HEK293-C34 cells were counted for 48 hours after seeding. (B) Degradation rate of SARS-CoV-2. Virus titers were determined every 12 hours during incubation at 37°C. (PPTX)
Shiho Torii (12770667), Yong Dam Jeong (14846302), Kei Sato (493447), Rigel Suzuki (12770673), Kwang Su Kim (1960972), Jumpei Ito (761675), Hiroyuki Asakura (1617940), Teppei Shimamura (133856), Takasuke Fukuhara (673475), Yasuhisa Fujita (10344689), Shoya Iwanami (3945266), Kazuhisa Yoshimura (322429), Kenji Sadamasu (7438220), Jun Koseki (738263), Yoshiharu Matsuura (357989), Shingo Iwami (266092), Mami Nagashima (14846305)   +16 more
core   +1 more source

Cell engineering for the production of hybrid-type N-glycans in HEK293 cells

The Journal of Biochemistry, 2021
Abstract Glycoprotein therapeutics are among the leading products in the biopharmaceutical industry. The heterogeneity of glycans in therapeutic proteins is an issue for maintaining quality, activity and safety during bioprocessing. In this study, we knocked out genes encoding Golgi α-mannosidase-II, MAN2A1 and MAN2A2 in human embryonic ...
Ji-Xiong Leng, Wei-Wei Ren, Yuqing Li, Ganglong Yang, Xiao-Dong Gao, Morihisa Fujita   +5 more
openaire   +2 more sources

Green Platinum Nanoparticles Interaction With HEK293 Cells: Cellular Toxicity, Apoptosis, and Genetic Damage

Dose-Response, 2018
Metal nanoparticles are widely used in industry, agriculture, textiles, drugs, and so on. The adverse effect of green platinum nanoparticles on human embryonic kidney (HEK293) cells is not well established.
Rafa S. Almeer, Daoud Ali, Saud Alarifi, Saad Alkahtani, Mansour Almansour   +4 more
doaj   +1 more source

HEK293S Cells Have Functional Retinoid Processing Machinery [PDF]

The Journal of General Physiology, 2002
Rhodopsin activation is measured by the early receptor current (ERC), a conformation-associated charge motion, in human embryonic kidney cells (HEK293S) expressing opsins. After rhodopsin bleaching in cells loaded with 11-cis-retinal, ERC signals recover in minutes and recurrently over a period of hours by simple dark adaptation, with no added ...
Brueggemann, Lioubov I., Sullivan, Jack M.   +1 more
openaire   +2 more sources

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO2.
Abhishek Albert, Vidhi Tiwari, Eldho Paul, Divya Ganesan, Mahesh Ayyavu, Ritu Kujur, Sasikumar Ponnusamy, Kathiresan Shanmugam, Luciano Saso, Selvam Govindan Sadasivam   +9 more
doaj   +1 more source

Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10

Journal of Pharmacological Sciences, 2022
OAT10 (SLC22A13) is a transporter highly expressed in renal tubules and transporting organic anions including nicotinate, β-hydroxybutyrate, p-aminohippurate, and orotate. In transport assays using Xenopus oocytes and HEK293 cells, we found that apparent
Naoko Ohtsu, Ryuichi Ohgaki, Chunhuan Jin, Minhui Xu, Hiroki Okanishi, Ryo Takahashi, Akiko Matsui, Wataru Kishimoto, Naoki Ishiguro, Yoshikatsu Kanai   +9 more
doaj   +1 more source

6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist

Biomolecules, 2022
P2X7 is an extracellular adenosine 5′-triphopshate (ATP)-gated cation channel present on leukocytes, where its activation induces pro-inflammatory cytokine release and ectodomain shedding of cell surface molecules.
Peter Cuthbertson, Amal Elhage, Dena Al-Rifai, Reece A. Sophocleous, Ross J. Turner, Ashraf Aboelela, Hiwa Majed, Richard S. Bujaroski, Iman Jalilian, Michael J. Kelso, Debbie Watson, Benjamin J. Buckley, Ronald Sluyter   +12 more
doaj   +1 more source

A cell function study on calcium regulation of a novel calcium-sensing receptor mutation (p.Tyr825Phe) [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2021
Purpose Autosomal dominant hypocalcemia with hypercalciuria is a genetic disease characterized by hypoparathyroidism with hypercalciuria. We discovered a novel variant (p.Tyr825Phe[Y825F]) of the CASR gene in a neonate with congenital hypoparathyroidism ...
Jung Eun Moon, Hee-Young Yang, Gabbine Wee, Suk-Hyun ParK, Cheol Woo Ko   +4 more
doaj   +1 more source

Protective effects of vitamin C on polyethylene terephthalate nanoplastic–induced oxidative stress and membrane damage: An in vitro study [PDF]

Journal of Preventive and Complementary Medicine
Background: Nanoplastics originating from polyethylene terephthalate (PET) are increasingly found in environmental and biological samples, where they have been linked to oxidative stress-driven cell injury.
Sogand Heydarian, Amir Nili-Ahmadabadi, Fereshteh Mehri, Akram Ranjbar   +3 more
doaj   +1 more source

A cell model to study different degrees of Hsp60 deficiency in HEK293 cells [PDF]

Cell Stress and Chaperones, 2011
Mitochondrial dysfunction is associated with neurodegenerative diseases and mutations in the HSPD1 gene, encoding the mitochondrial Hsp60 chaperone, are the causative factors of two neurodegenerative diseases, hereditary spastic paraplegia and MitChap60 disease.
Bie, Anne Sigaard, Palmfeldt, Johan, Hansen, Jakob, Christensen, Rikke, Gregersen, Niels, Corydon, Thomas Juhl; id_orcid 0000-0003-3588-6350, Bross, Peter; id_orcid 0000-0001-9526-8525   +6 more
openaire   +3 more sources