Results 21 to 30 of about 150,776 (304)

Effects of Fish Oil Combined with Cisplatin on HEK293 Cells and A549 Cells

open access: yesShipin gongye ke-ji, 2022
Objective: To explore the effect of fish oil on the activity of cis-dichlorodiamineplatinum (Ⅱ) (CDDP) against A549 human lung adenocarcinoma cells and its protective effect on HEK293 cells damaged by CDDP. Methods: A549 and HEK293 cells were cultured in
Yuemei DU   +3 more
doaj   +1 more source

The toxicogenic effect of Terminalia phanerophlebia Engl. & Diels leaf extract on oxidative stress parameters in an in vitro Hek293 model [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: Medicinal plants are a highly sought-after alternative to current pharmaceutical drugs because they can be locally cultivated, inexpensive and possess minimal adverse effects.
Marcilyn R. Nyahada   +5 more
doaj  

CD133 induces tumour-initiating properties in HEK293 cells [PDF]

open access: yesTumor Biology, 2012
The pentaspan protein CD133 (Prominin-1) is part of the signature of tumour-initiating cells for various cancer entities. The aim of the present study was to investigate the impact of ectopic CD133 expression on tumourigenic properties of otherwise CD133-negative, non-tumourigenic cells in vitro and in vivo.
Canis   +8 more
openaire   +3 more sources

Aspect ratios of transfected HEK293 cells.

open access: yes, 2021
Aspect ratios of transfected HEK293 cells.
Angel M. Aponte (2213821)   +3 more
core   +1 more source

Myricetin inhibits Kv1.5 channels in HEK293 cells

open access: yesMolecular Medicine Reports, 2015
Myricetin (Myr) is a flavonoid that exerts anti-arrhythmic effects. However, its potential effects on ion channels have remained elusive. The aim of the present study was to investigate the effects of Myr on Kv1.5 channels in HEK293 cells. The current of Kv1.5 channels (Ikur) in HEK293 cells was recorded using the whole-cell patch-clamp technique and ...
Xianhong, Ou   +6 more
openaire   +3 more sources

Culture of HEK293-EBNA1 Cells for Production of Recombinant Proteins [PDF]

open access: yesCold Spring Harbor Protocols, 2008
INTRODUCTIONFast and efficient production of recombinant proteins (r-proteins) remains a major challenge for the academic and biopharmaceutical communities. Pure r-proteins are often required in large amounts (hundreds of milligrams to gram quantities) when being developed as biotherapeutics, or in smaller quantities (milligrams) for high-throughput ...
Roseanne, Tom   +2 more
openaire   +2 more sources

The aminopeptidase B (Ap-B) is phosphorylated in HEK293 cells

open access: yesBiochimie, 2022
Proteolysis is a post-translational modification (PTM) that affects the whole proteome. First regarded as only destructive, it is more precise than expected. It is finely regulated by other PTMs like phosphorylation. Aminopeptidase B (Ap-B), a M1 metallopeptidase, hydrolyses the peptide bond on the carbonyl side of basic residues at the NH2-terminus of
Emilie Adicéam   +4 more
openaire   +2 more sources

Cell engineering for the production of hybrid-type N-glycans in HEK293 cells

open access: yesThe Journal of Biochemistry, 2021
Abstract Glycoprotein therapeutics are among the leading products in the biopharmaceutical industry. The heterogeneity of glycans in therapeutic proteins is an issue for maintaining quality, activity and safety during bioprocessing. In this study, we knocked out genes encoding Golgi α-mannosidase-II, MAN2A1 and MAN2A2 in human embryonic ...
Ji-Xiong Leng   +5 more
openaire   +2 more sources

Generation of Mt BART(+/−)·S13- HEK293-EBV cells.

open access: yes, 2023
A) Schematic diagram of BART(+/-)·S13+ EBV bacmids. A CTCF-binding site on the BART miRNA promoter was identified as BARTp CTCF BS. B) Sequences introduced at the points of recombination to introduce site-directed mutations at the S13 locus (EBV 138963 ...
Sora Huh (14504838)   +11 more
core   +1 more source

Functional coupling of organic anion transporter OAT10 (SLC22A13) and monocarboxylate transporter MCT1 (SLC16A1) influencing the transport function of OAT10

open access: yesJournal of Pharmacological Sciences, 2022
OAT10 (SLC22A13) is a transporter highly expressed in renal tubules and transporting organic anions including nicotinate, β-hydroxybutyrate, p-aminohippurate, and orotate. In transport assays using Xenopus oocytes and HEK293 cells, we found that apparent
Naoko Ohtsu   +9 more
doaj   +1 more source

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