Results 51 to 60 of about 132,829 (164)
Nanomaterials, 2019 Graphene, a two-dimensional carbon sheet with single-atom thickness, shows immense promise in several nanoscientific and nanotechnological applications, including in sensors, catalysis, and biomedicine.
Sangiliyandi Gurunathan +12 more
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Culture of HEK293-EBNA1 Cells for Production of Recombinant Proteins [PDF]
Cold Spring Harbor Protocols, 2008 INTRODUCTIONFast and efficient production of recombinant proteins (r-proteins) remains a major challenge for the academic and biopharmaceutical communities. Pure r-proteins are often required in large amounts (hundreds of milligrams to gram quantities) when being developed as biotherapeutics, or in smaller quantities (milligrams) for high-throughput ...
Roseanne, Tom +2 more
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Substance P induces rapid and transient membrane blebbing in U373MG cells in a p21-activated kinase-dependent manner. [PDF]
PLoS ONE, 2011 U373MG astrocytoma cells endogenously express the full-length neurokinin 1 receptor (NK1R). Substance P (SP), the natural ligand for NK1R, triggers rapid and transient membrane blebbing and we report that these morphological changes have different ...
John Meshki +4 more
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Frontiers in Oncology, 2020 In this study, we investigated the efficacy of methyl-cantharidimide (MCA), a cantharidin (CTD) analog, as an anticancer drug, in cancer cells overexpressing either ABCB1 or ABCG2 transporters and in cisplatin-resistant cancer cells.
Yi-Dong Li +10 more
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Overexpression of G-protein-coupled receptor 40 enhances the mitogenic response to epoxyeicosatrienoic acids. [PDF]
PLoS ONE, 2015 The cytochrome P450 epoxygenase-dependent arachidonic acid metabolites, epoxyeicosatrienoic acids (EETs), are potent survival factors and mitogens for renal epithelial cells, but the molecular identity in the cells that initiates the mitogenic signaling ...
Seong Kwon Ma +5 more
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HEK293 cell culture for co-immunoprecipitation experiments v1
, 2023 Here, we describe HEK293 cell culture for the purpose of co-immunoprecipitation experiments
Dan Dou, Erika Holzbaur
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Nicotinic acetylcholine receptor (CHRN) expression and function in cultured human adult fungiform (HBO) taste cells. [PDF]
PLoS ONE, 2018 In rodents, CHRNs are involved in bitter taste transduction of nicotine and ethanol. Currently, it is not clear if CHRNs are expressed in human taste cells and if they play a role in transducing the bitter taste of nicotine and ethanol or in the ...
Jie Qian +6 more
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Small RNA Analysis in Sindbis Virus Infected Human HEK293 Cells
PLoS ONE, 2013 In contrast to the defence mechanism of RNA interference (RNAi) in plants and invertebrates, its role in the innate response to virus infection of mammals is a matter of debate. Since RNAi has a well-established role in controlling infection of the alphavirus Sindbis virus (SINV) in insects, we have used this virus to investigate the role of RNAi in ...
Donaszi-Ivanov, Andras +3 more
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Medical Sciences, 2018 Creating efficient cell lines is a priority for the biopharmaceutical industry, which produces biologicals for various uses. A recent approach to achieving this goal is the use of non-coding RNAs, microRNA (miRNA) and small interfering RNA (siRNA), to ...
Laura Abaandou, Joseph Shiloach
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Journal of Mazandaran University of Medical Sciences, 2017 Background and purpose: Endothelial growth factor type b with anti-angiogenic activity and inhibition of tumor growth are considered as new anticancer drugs.
Morteza Sadeghi, Zohreh Hojati
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