Results 141 to 150 of about 215,192 (350)

Coupling of Two Motor Proteins: a New Motor Can Move Faster [PDF]

, 2005
We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is presented.
Anatoly B. Kolomeisky, D. Bray, Evgeny B. Stukalin, Hubert Phillips, J. Howard, P. W. Finch, P. W. Finch, P. W. Finch, T. T. Perkins   +8 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization [PDF]

, 2013
The origin recognition complex (ORC) of Saccharomyces cerevisiae binds origin DNA and cooperates with Cdc6 and Cdt1 to load the replicative helicase MCM2–7 onto DNA. Helicase loading involves two MCM2–7 hexamers that assemble into a double hexamer around
A. Fernandez-Cid, A. Riera, Bell, Bowers, Bray, C. Evrin, C. Speck, Casas-Terradellas, Chen, Cocker, Coleman, Costa, Donovan, Dueber, Gillespie, Herbig, Holm, J. Zech, Klemm, Krupinski, Laemmli, Liang, Liang, Liu, M. C. Herrera, Mizushima, Neuwald, P. Clarke, Perkins, R. Lurz, Randell, Remus, Remus, Roy, S. Brill, Schepers, Seki, Singleton, Steven, Stoeber, Takara, Tanaka, Watanabe, Weinreich, Wendler, Williams, Ying, Zhang   +47 more
core   +1 more source

DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches

, 2022
Annalaura Brai, Claudia Immacolata Trivisani, Federica Poggialini, Claudia Pasqualini, Chiara Vagaggini, Elena Dreassi   +5 more
openalex   +1 more source

The Chd4 Helicase Regulates Chromatin Accessibility and Gene Expression Critical for β-Cell Function In Vivo [PDF]

, 2023
Rebecca K. Davidson, Sukrati Kanojia, Wenting Wu, Tatsuyoshi Kono, Zhiwei Xu, Meredith Osmulski, Robert N. Bone, Nolan Casey, Carmella Evans‐Molina, Emily K. Sims, Jason M. Spaeth   +10 more
openalex   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

Journal of Cell Biology, 2015
BLM helicase facilitates telomere replication by resolving G-quadruplex structures that can form in the G-rich repeats during leading strand synthesis.
W. C. Drosopoulos, Settapong T. Kosiyatrakul, C. Schildkraut   +2 more
semanticscholar   +1 more source

ruvA Mutants that resolve Holliday junctions but do not reverse replication forks [PDF]

, 2008
RuvAB and RuvABC complexes catalyze branch migration and resolution of Holliday junctions (HJs) respectively. In addition to their action in the last steps of homologous recombination, they process HJs made by replication fork reversal, a reaction which ...
A Blastyak, A Constantinou, A Kuzminov, A Machwe, Alison Sylvia Bradley, B Guenther, B Michel, B Michel, Bénédicte Michel, C Ralf, CA Parsons, CE Shurvinton, CV Privezentzev, CZ Bachrati, D Chamberlain, D Hargreaves, DV Bugreev, EC Friedberg, EP Rocha, F Lecointe, F Osman, F Osman, G Grompone, H Iwasaki, H Shinagawa, IR Tsaneva, IR Tsaneva, Irina Tsaneva, JB Rafferty, JH Miller, JK Karow, JR Donaldson, K Hiom, K Yamada, K Yamada, L Wu, M Ariyoshi, M Fromant, M Lopes, M Oram, M Seigneur, Marie Le Masson, MC Whitby, MC Whitby, ME Robu, MJ Flores, P McGlynn, P McGlynn, P McGlynn, P McGlynn, R Lestini, RC Heller, RG Lloyd, SC West, SD Vincent, SM Roe, SN Chan, T Hishida, T Hishida, T Nishino, T Nishino, T Shibata, TN Mandal, W Bussen, William F. Burkholder, Y Liu, Y Liu, Z Baharoglu, Zeynep Baharoglu   +68 more
core   +3 more sources

MOV10 Is a 5′ to 3′ RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3′ UTRs [PDF]

, 2014
Lea H. Gregersen, Markus Schueler, Mathias Munschauer, Guido Mastrobuoni, Wei Chen, Stefan Kempa, Christoph Dieterich, Markus Landthaler   +7 more
openalex   +1 more source

The G-patch activators Pfa1 and PINX1 exhibit different modes of interaction with the Prp43 RNA helicase [PDF]

, 2020
Saïda Mouffok, Régine Capeyrou, Kamila Belhabich-Baumas, Clément Joret, Anthony K. Henras, Odile Humbert, Yves Henry   +6 more
openalex   +1 more source