Results 201 to 210 of about 194,742 (384)
Compartmentalisation in cAMP signalling: A phase separation perspective
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
The mechanism of eukaryotic CMG helicase activation
M. Douglas+3 more
semanticscholar +1 more source
A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity. [PDF]
Michael Altmann+5 more
openalex +1 more source
We have uncovered a novel mechanism by which HROB modulates cell proliferation in lung adenocarcinoma. Our findings suggest that HROB recruits ZC3HC1 and mediates its de‐phosphorylation at Ser354, which in turn promotes K27‐linked ubiquitination of CCNB1, leading to its proteasomal degradation.
Zhe Zhang+12 more
wiley +1 more source
An expanding family of helicases within the “DEAD/H” superfamily [PDF]
Peer Bork, Eugene V. Koonin
openalex +1 more source
Nucleolar Organization in Response to Transcriptional Stress
In this review, we provide an overview of the research field on nucleolar regulation, mainly focusing on nucleolar organization under transcriptional stress. We also highlight the importance of ribosomal DNA stability, particularly in disease prevention, including cancer.
Rikiya Imamura, Takaaki Yasuhara
wiley +1 more source